食品科学

• 工艺技术 • 上一篇    下一篇

葛根螺旋藻复合片配方和生产工艺优化

杨生辉,罗光宏*,祖廷勋,王丹霞,陈天仁   

  1. 河西学院凯源生物技术开发中心,甘肃省微藻工程技术研究中心,甘肃 张掖 734000
  • 出版日期:2014-07-25 发布日期:2014-08-26
  • 通讯作者: 罗光宏
  • 基金资助:

    2014年甘肃省农业领域知识产权优势企业培育项目(14OPIPG002);2014年甘肃省高等学校科研项目(2014A-109;
    2014B-086);2013年甘肃省第四批科技计划项目(1304FKCG1033);甘肃省工程技术研究中心专项(1009FTGG017)

Optimization of Formulation and Processing of Puerariae Radix Extract-Spirulina Compound Tablets

YANG Sheng-hui, LUO Guang-hong*, ZU Ting-xun, WANG Dan-xia, CHEN Tian-ren   

  1. Kai-yuan Biotechnology Development Center, Gansu Engineering Research Center for Microalgae, Hexi University, Zhangye 734000, China
  • Online:2014-07-25 Published:2014-08-26
  • Contact: LUO Guang-hong

摘要:

以螺旋藻粉和葛根提取物为主要原料,通过单因素和正交试验,经过方差分析,结合极差结果,筛选出
最佳配方,采用直接压迫成型制片工艺,生产葛根螺旋藻复合片。研究结果表明,赋形剂最佳配方用量为二氧
化硅1.5%、微晶纤维素1%、硬脂酸镁0.25%;葛根螺旋藻复合片最佳配方为葛根提取物用量10%、螺旋藻粉用量
87.5%、赋形剂用量2.5%、螺旋藻粉含水量约7.5%、制片压力30 kN。

关键词: 葛根螺旋藻复合片, 配方, 生产工艺

Abstract:

Puerariae Radix-Spirulina compound tablets were made from Puerariae Radix extract (rich in flavonoids) and
Spirulina powder by direct pressing method. The formulation was optimized by single-factor and orthogonal array designs
through analysis of variance (ANOVA) and range analysis. The results obtained in this research showed that the optimum
excipient consisted of 1.5% silicon dioxide, 1% microcrystalline cellulose and 0.25% magnesium stearate, and the optimum
tablet formulation was composed of 10% Puerariae Radix extract, 87.5% Spirulina powder with a moisture content of about
7.5% and 2.5% excipient. The tableting pressure was 30 kN.

Key words: Puerariae Radix-Spirulina compound tablets, formulation, process

中图分类号: