食品科学

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牛、羊乳及其乳制品中幽门螺杆菌污染及检测技术研究进展

张 于,江 涛,冉 健,文月玲,沈留红,余树民,曹随忠,姚学萍*   

  1. 四川农业大学动物医学院,动物疫病与人类健康四川省重点实验室,四川 雅安 625014
  • 出版日期:2015-01-15 发布日期:2015-01-16

Recent Progress in Contamination and Detection Techniques of Helicobacter pylori in Milk and Dairy Products

ZHANG Yu, JIANG Tao, RAN Jian, WEN Yueling, SHEN Liuhong, YU Shumin, CAO Suizhong, YAO Xueping*   

  1. Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine,Sichuan Agricultural University, Ya’an 625014, China
  • Online:2015-01-15 Published:2015-01-16

摘要:

近年来大量研究已经表明幽门螺杆菌(Helicobacter pylori,Hp)可能是种食源性致病菌,而牛、羊乳是其最可能的感染源。食物中较难分离培养出Hp,而聚合酶链式反应相关技术灵敏度高,能检出样品中微量的Hp,可用于检测牛、羊乳中幽门螺杆菌的污染情况,但是与人类临床方面检测Hp技术的多样性、特异性与成熟性相比,食品中Hp快速而有效的检测方法及相关标准还相对缺乏。本文主要就近年来牛、羊乳及其乳制品中幽门螺杆菌污染及检测技术的研究进展进行综述,为进一步完善Hp传播途径与致病机制等研究提供一些参考。

关键词: 幽门螺杆菌, 牛乳, 乳制品, 检测技术

Abstract:

In recent years, a large number of studies have shown that Helicobacter pylori may be a food-borne pathogen,
and milk is one of the most likely sources of its infection. Isolation and culture of H. pylori from food samples is exacting
and time-consuming. At present, PCR and related technologies, which have high sensitivity, are applied to detect trace
amounts of H. pylori in food samples such as milk. However, there is lack of rapid and effective detection methods and
related standards for H. pylori in food samples although a variety of specific and mature assays are currently available for
clinical use. This review focuses on recent progress in contamination and detection techniques of H. pylori in milk and dairy
products, so as to provide some references for further research on transmission and pathogenic mechanisms of H. pylori.

Key words: Helicobacter pylori, cow’s milk, dairy products, detection techniques

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