食品科学

• 专题论述 • 上一篇    下一篇

吡咯喹啉醌研究新进展

唐 靓,张 岭,李林子,王 茵*   

  1. 浙江省医学科学院,浙江 杭州 310013
  • 出版日期:2015-10-15 发布日期:2015-10-20

Lastest Progress in Research on Pyrroloquinoline Quinone

TANG Liang, ZHANG Ling, LI Linzi, WANG Yin*   

  1. Zhejiang Academy of Medical Sciences, Hangzhou 310013, China
  • Online:2015-10-15 Published:2015-10-20

摘要:

吡咯喹啉醌(pyrroloquinoline quinone,PQQ)是细菌脱氢酶中的一种氧化还原辅助因子,又是一种抗氧化剂,能避免细胞内氧化反应以及体外生物活性物质产生活性氧导致的细胞损伤,为细胞的生长发育提供营养与维生素,同时使细胞具有抗氧化的耐受性。它对植物病原真菌起到生物控制剂的作用,能诱导蛋白激酶参与哺乳动物细胞分化发育过程。PQQ能通过增加不溶性磷酸盐的利用率来提高作物产量,它与氧化还原循环功能有很强相关性,具有抗神经退行性、抗癌、信号传导等功能。

关键词: 吡咯喹啉醌, 氧化还原, 神经细胞保护, 信号转导

Abstract:

Pyrroloquinoline quinine (PQQ) is a redox cofactor of bacterial dehydrogenase and an antioxidant. It can prevent
oxidative reaction in vivo and cell damage caused by reactive oxygen species from biological active substances in vitro,
to provide nutrients and vitamins for cell growth. PQQ is a biological control agent for plant fungal pathogens, which
can induce protein kinase to play a part in the development of mammalian cell differentiation. PQQ can improve the crop
productivity by increasing the utilization rate of insoluble phosphate, which has close correlation with redox recycling
function as an anti-neurodegenerative, anticancer and pharmacological agent.

Key words: pyrroloquinoline quinone, redox, neuron protection, signal transduction

中图分类号: