食品科学

• 专题论述 • 上一篇    

量子点标记免疫技术在食品中小分子有害物检测中的应用

戴尽波   

  1. 广东顺德工业设计研究院(广东顺德创新设计研究院),广东 佛山 528311
  • 出版日期:2016-10-15 发布日期:2016-12-01

A Review of the Application of Quantum Dots as Probes in Fluorescent Immunoassays of Low Molecular Weight Food Contaminants

DAI Jinbo   

  1. Guangdong Shunde Industrial Design Institute(Guangdong Shunde Innovative Design Institute), Foshan 528311, China
  • Online:2016-10-15 Published:2016-12-01

摘要:

量子点(quantum dots,QDs)是一种荧光纳米颗粒,具有荧光量子产率高、发射光谱窄、发射波长可调等优点,是近几年发展起来的一种新型荧光标记物,在食品中小分子有害物免疫检测中的应用已成为研究热点。本文总结介绍了3 种常用的QDs与抗体/抗原偶联方法及其各自优缺点,并对基于QDs的荧光免疫分析方法在食品小分子有害物检测中的应用进行了详细综述。

关键词: 量子点, 偶联, 食品安全, 小分子, 荧光免疫分析

Abstract:

Quantum dots (QDs) are semiconductor nanoparticles with very interesting optical properties like high quantum
yield, and narrow and size-tunable fluorescence spectra. QDs are applied widely, especially as fluorescence labels in food
safety detection that has received increased attention recently. In this review, three methods for coupling antibody/antigen
to QDs are discussed. The development of QD-based fluorescent immunoassays for the detection of low molecular weight
hazardous compounds in the food safety area is also demonstrated.

Key words: quantum dots, conjugation, food safety, low molecular weight compounds, fluorescent immunoassays

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