食品科学 ›› 2018, Vol. 39 ›› Issue (21): 149-154.doi: 10.7506/spkx1002-6630-201821022

• 营养卫生 • 上一篇    下一篇

兰坪虫草的缓解运动疲劳功能

孔 娜1,虞 泓2,3,张艳艳1,葛 锋1,3,*   

  1. 1.昆明理工大学生命科学与技术学院,云南 昆明 650500;2.云南大学中草药生物资源研究所云百草实验室,云南 昆明 650091;3.昆明市虫草生物资源开发利用工程技术研究中心,云南 昆明 650091
  • 出版日期:2018-11-15 发布日期:2018-11-21
  • 基金资助:
    国家自然科学基金地区科学基金项目(81560616)

Sport Fatigue-Alleviating Effect of Ophiocordyceps lanpingensis

KONG Na1, YU Hong2,3, ZHANG Yanyan1, GE Feng1,3,*   

  1. 1. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China; 2. Yunnan Herbal Laboratory, Institute of Herb Biotic Resources, Yunnan University, Kunming 650091, China; 3. The Research Center of Cordyceps Development and Utilization of Kunming, Kunming 650091, China
  • Online:2018-11-15 Published:2018-11-21

摘要: 目的:研究兰坪虫草对小鼠运动的抗疲劳效果。方法:小鼠随机分为5 个实验组,分别为兰坪虫草低剂量组(450 mg/(kg·d))、中剂量组(900 mg/(kg·d))、高剂量组(1 800 mg/(kg·d))以及空白组(蒸馏水)、阳性对照组(西洋参600 mg/(kg·d)),连续灌胃30 d,研究兰坪虫草对小鼠负重游泳时间、血乳酸、血清尿素氮、肝糖原、抗氧化酶、血液相关参数等疲劳指标的影响。结果:各剂量组兰坪虫草均能显著延长小鼠负重游泳时间(P<0.05);中、高剂量组可以显著降低小鼠运动后血清尿素氮浓度(P<0.05);高剂量组和阳性对照组能显著提高小鼠体内肝糖原的储备量(P<0.05);同时,兰坪虫草能提高血液血红蛋白和血糖浓度,明显增加抗氧化酶的活力,降低丙二醛水平。结论:研究证明兰坪虫草具有缓解小鼠运动疲劳的作用。

关键词: 兰坪虫草, 抗疲劳, 抗氧化, 兰坪虫草

Abstract: Objective: To investigate the anti-fatigue effect of Ophiocordyceps lanpingensis (OL) in mice. Methods: Mice were randomly divided into five groups: negative control (orally administered with distilled water), positive control (administered with 600 mg/(kg·d mb) of American ginseng) and OL low-, medium- and high-dose (gavaged with OL powder at doses of 450, 900, and 1 800 mg/(kg·d mb) , respectively) groups. After administration for 30 days, the weight-loading swimming time as well as blood lactic acid, blood urea nitrogen (BUN), glycogen (LG) and antioxidant enzyme activities and other fatigue-related blood parameters in the mice were determined. Results: Ophiocordyceps lanpingensis could increase the weight-loading swimming time of mice at all doses (P < 0.05); the mice from the middle- and high-dose group showed significantly reduced levels of BUN after exercise (P < 0.05); the mice from the high-dose group and the positive control group could significantly improve LG level (P < 0.05). Meanwhile, Ophiocordyceps lanpingensis improved blood hemoglobin and blood sugar levels, increased the activity of antioxidant enzymes, and reduced blood malondialdehyde content. Conclusion: Ophiocordyceps lanpingensis has an anti-fatigue effect in mice.

Key words: Ophiocordyceps lanpingensis, anti-fatigue, anti-oxidant, Ophiocordyceps lanpingensis

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