食品科学 ›› 2020, Vol. 41 ›› Issue (13): 242-248.doi: 10.7506/spkx1002-6630-20190423-309

• 专题论述 • 上一篇    下一篇

亚麻籽调节糖脂代谢作用的研究进展

史湘铃,孙桂菊   

  1. (东南大学公共卫生学院营养与食品卫生学系,环境医学工程教育部重点实验室,江苏 南京 210009)
  • 出版日期:2020-07-15 发布日期:2020-07-29
  • 基金资助:
    国家自然科学基金面上项目(81872618)

Recent Progress in the Regulation of Glycolipid Metabolism by Flaxseeds

SHI Xiangling, SUN Guiju   

  1. (Key Laboratory of Environmental Medicine Engineering, Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, China)
  • Online:2020-07-15 Published:2020-07-29

摘要: 赤霉素(gibberellins,GAs)是一类在植物体内广泛存在的植物激素,在植物生长、发育以及对环境胁迫的反应中起着至关重要的作用。GAs是一类四环二萜酸,其基本结构是二十碳赤霉烷。到目前为止,已发现的GAs多达136 种。随着近年来GAs在农业生产中的广泛使用以及相关毒性的深入研究,由GAs引起的食品安全问题得到越来越多的关注。GAs精准分析技术有助于深入解析GAs代谢行为及其生理活性与毒性。由于GAs的不稳定性及其极低的含量(一般为ng/g,甚至为pg/g水平),复杂基质中GAs分析的前处理技术和分析手段经历了不断更新与提升的过程。本文综述了过去10 年GAs痕量分析中前处理技术和分析手段上的发展与突破,并展望了复杂基质中GAs分析技术发展趋势。

关键词: 赤霉素, 色谱-质谱, 痕量分析, 前处理技术, 分析手段

Abstract: Flax, a crop of great economic importance, is widely utilized as the most abundant source of alpha-linolenic acid and lignans. Many studies have reported that flaxseeds have many functions such as lowering blood lipid and blood glucose and improving insulin resistance and therefore have been of great interest to researchers. In this paper, the biological effects of flaxseeds on glucose and lipid metabolism are reviewed and the possible molecular mechanisms are analyzed so as to provide a reliable basis for applying flaxseeds in the prevention and treatment of chronic diseases such as obesity, hyperlipidemia and diabetes mellitus.

Key words: flaxseed, glycolipid metabolism, molecular mechanism

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