α-生育酚琥珀酸单酯制取工艺研究

食品科学 ›› 2005, Vol. 26 ›› Issue (4): 160-163.

α-生育酚琥珀酸单酯制取工艺研究

孙登文, 牛东, 惠伯棣

清华大学化学工程系；北京联合大学应用文理学院

出版日期:2005-04-15 发布日期:2011-09-19

Study on the Process of Producing α-tocopherol Acid Succinate

SUN Deng-Wen, NIU Dong, HUI Bo-Di

1.Department of Chemical Engineering, Tsinghua University; 2.College of Applied Arts and Sciences, Beijing Union University

Online:2005-04-15 Published:2011-09-19

摘要/Abstract

摘要： α-生育酚琥珀酸单酯是维生素E商品的一种,具有多种药理功能。本文通过单因素实验和正交实验,研究了利用人工合成的α-生育酚和琥珀酸酐制取α-生育酚琥珀酸单酯的工艺。在优化工艺条件下,α-生育酚的酯化率达90%以上。

关键词: α-生育酚琥珀酸单酯

Abstract: α-Tocopherol acid succinate is one of the important Vitamin E products and has a number of medical functions. This paper outlines the process development of α-tocopherol acid succinate synthesis by a single factor and orthogonal design experiments in which α-tocopherol reacted with the succinic anhydride. With this process, the esterification of α-tocopherol could exceed 90% by weight under optimum conditions.

Key words: α-tocopherol acid succinate

孙登文, 牛东, 惠伯棣. α-生育酚琥珀酸单酯制取工艺研究[J]. 食品科学, 2005, 26(4): 160-163.

SUN Deng-Wen, NIU Dong, HUI Bo-Di. Study on the Process of Producing α-tocopherol Acid Succinate[J]. FOOD SCIENCE, 2005, 26(4): 160-163.