食品科学 ›› 2007, Vol. 28 ›› Issue (8): 348-350.

• 分析检测 • 上一篇    下一篇

丹参中丹参素的含量测定

 潘见, 周蓓蓓, 开桂青, 金日生   

  1. 合肥工业大学农产品生物化工教育部工程技术研究中心; 合肥工业大学农产品生物化工教育部工程技术研究中心 安徽合肥230009; 安徽合肥230009;
  • 出版日期:2007-08-15 发布日期:2011-10-24

Quantitative Determination of Salvianic acid A in Salvia miltiorrhiza Bge by HPLC

 PAN  Jian, ZHOU  Bei-Bei, KAI  Gui-Qing, JIN  Ri-Sheng   

  1. Engineering Research Center of Bio-process, Ministry of Education, Hefei University of Technology, Anhui 230009, China
  • Online:2007-08-15 Published:2011-10-24

摘要: 丹参素(Salvianic acid A)是一种水溶性酚酸类化合物,又名丹参酸甲,其常用制剂主要用于治疗心脑血管疾病,为了最大限度的除去其他杂质成分的干扰,更准确的测定丹参中丹参素的含量,往HPLC的流动相(甲醇:0.5%冰醋酸=1:6)中加入1mmol/L的硼砂,发现流动相中加入硼砂后在281nm处进行测定发现峰形最好。方法快速简便,可以作为丹参素分离检测的一种依据。

关键词: 丹参素, HPLC, 硼砂

Abstract: Salvianic acid A in Salvia mitiorrhiza Bge a kind of water-soluble hydroxybenzene acid. Same as another name Salvia miltiorrhiza Bge acid. Its preparation is always used to treat the disease of blood vessels of heart and cerebra. 1mmol/L borax was added into the mobile phase (methanol:0.5% acetic acid=1:6) for getting hold of more pure Salvianic acid A. 281nm was detected and found that the peak is optimal. The method is simple for characterizing,purifing and determinating the Salvianic acid A.

Key words: Salvianic acid A, HPLC, borax