食品科学 ›› 2007, Vol. 28 ›› Issue (8): 468-470.

• 营养卫生 • 上一篇    下一篇

苹果多酚的促排铅功效研究

 艾志录, 王育红, 塔西买买提·马合苏木, 王娜, 李建新   

  1. 河南农业大学食品科学技术学院; 伊犁师范学院生物化学与环境科学学院; 河南农业大学食品科学技术学院 河南郑州450002; 河南郑州450002; 新疆伊宁835000;
  • 出版日期:2007-08-15 发布日期:2011-10-24

Study on Effects of Apple Polyphenols on Lead Discharging in Mice

 AI  Zhi-Lu, WANG  Yu-Hong, TA  Xi-Mai-Mai-Ti-·Ma-He-Su-Mu, WANG  Na, LI  Jian-Xin   

  1. 1.College of Food Science and Technology, Henan Agricultural University, Zhengzhou 450002, China; 2.College of Biochemistry and Environment Science, Yili Normal University, Yining 835000, China
  • Online:2007-08-15 Published:2011-10-24

摘要: 采用小鼠腹腔注射乙酸铅溶液10d,建立染铅小鼠模型,连续15d灌胃给予苹果多酚,研究苹果多酚的促排铅作用。石墨炉原子吸收法测试血铅、尿铅、粪铅和股骨、肝脏中铅含量。结果表明:染毒小鼠给予苹果多酚后,血铅和股骨、肝脏中铅含量明显低于阳性对照组,而尿铅明显高于阳性对照组。苹果多酚具有明显的促排铅效果。

关键词: 铅中毒, 苹果多酚, 排铅

Abstract: The purpose of this paper was to evaluate the lead discharging effects of apple polyphenol (AP) on male Kunming mice given lead. Lead acetate was administered by intraperitoneal injection for 10 days. Administration of AP to mice by gastric incubation was performed for 15 days from the end of lead exposure up to the end of the experiment. Then, the mice were sacrificed for comparison of lead distribution. Concentrations of lead in the specimens were determinated by graphite furnace atomic absorption spectrophotometry. It was observed that the blood lead, the liver lead and the femur level significantly decreased, but urinates lead elimination significantly increased. The results illustrated that AP could discharge lead .

Key words:  , lead poisoning; apple polyphenol; lead discharging;