食品科学 ›› 2011, Vol. 32 ›› Issue (13): 374-378.doi: 10.7506/spkx1002-6630-201113081

• 专题论述 • 上一篇    

白藜芦醇及生物工程表达系统的研究概况

宋洋波1,刘延琳1,2,刘树文1,2,吴嘉慧1,惠竹梅1,2,*   

  1. 1.西北农林科技大学葡萄酒学院 2.陕西省葡萄与葡萄酒工程研究中心
  • 出版日期:2011-07-15 发布日期:2011-07-02
  • 基金资助:
    国家葡萄产业技术体系建设专项(CARS-30)

Advances in Research on Resveratrol and Its Biotechnological Expression Systems

SONG Yang-bo1,LIU Yan-lin1,2,LIU Shu-wen1,2,WU Jia-hui1,XI Zhu-mei1,2,*   

  1. (1. College of Enology, Northwest A & F University, Yangling 712100, China ; 2. Shaanxi Engineering Research Center for Viti-Viticulture, Yangling 712100, China)
  • Online:2011-07-15 Published:2011-07-02

摘要: 白藜芦醇是一种天然的植物保护素,它是许多植物受到真菌感染、紫外照射或病理状况下产生的一种植物抗毒素,可以提高植物抵抗病原体的能力,并且它也具有相当的生理活性,不但具有抗氧化、抗菌、调节血脂、抗癌的保健功能,而且研究证明白藜芦醇对于多种动物有延长寿命的功效。白藜芦醇在葡萄中的合成路径以及相关各酶的研究已经取得较好的进展。更重要的是,随着生物工程技术的发展,在植物、动物和微生物中合成白藜芦醇合酶的产物已不再困难。通过对近年来在不同表达系统中合成白藜芦醇的研究进行综述,提出利用生物工程技术来合成白藜芦醇所面对的问题及将来的发展方向。

关键词: 白藜芦醇, 生物工程, 表达系统

Abstract: Resveratrol is a natural phytoalexin, which is generated in plants due to fungal infections, ultraviolet illumination or pathological conditions. The phytoalexin enhances the resistance of plants against pathogens and has considerable physiological activities such as antioxidant, antimicrobial, blood lipid-regulating and anticancer functions. It has been shown to be able to prolong the lives of animals. Great advances have been made in the research on the synthesis pathway in grape and related enzymes. With the development of bioengineering technology, it is no longer difficult to express resveratrol synthase gene and synthesize resveratrol in plants, microbes and animals. This article reviews recent studies on the synthesis of resveratrol in different organisms. Meanwhile, problems and future directions for research into the synthesis of resveratrol by bioengineering technology are proposed.

Key words: resveratrol, bioengineering, expression system

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