食品科学 ›› 2013, Vol. 34 ›› Issue (1): 345-350.

• 专题论述 • 上一篇    

半连续发酵及其应用研究进展

孙文敬1,2,刘长峰1,2,周延政2,3,王大明4,崔凤杰1,2,余 琳1,2   

  1. 1.江苏大学食品与生物工程学院 2.江西省生物发酵食品添加剂工程技术研究中心 3.百勤异VC钠有限公司 4.河北师范大学生命科学学院
  • 收稿日期:2011-11-03 修回日期:2012-12-05 出版日期:2013-01-15 发布日期:2013-01-07
  • 通讯作者: 孙文敬 E-mail:sunwenjing1919@163.com
  • 基金资助:

    江西省科技条件平台建设项目;江西省优势科技创新团队计划项目;江西省主要学科学术和技术带头人培养计划项目;江苏大学科研启动基金项目

Recent Progress in Semi-continuous Fermentation and Its Application

  • Received:2011-11-03 Revised:2012-12-05 Online:2013-01-15 Published:2013-01-07

摘要: 半连续发酵是一种重要的生化培养方式。本文介绍半连续发酵的应用领域,详细综述半连续发酵的分类、特点、与连续发酵的联系以及半连续发酵过程中的菌体循环利用方法,并结合当前代谢工程和过程控制策略的发展趋势,对半连续发酵技术的应用前景进行展望。

关键词: 半连续发酵, 研究现状, 应用领域, 展望

Abstract: Semi-continuous fermentation technology is a typical operational model. In this article, we first introduced the application areas of semi-continuous fermentation, and then reviewed the classification and features of semi-continuous fermentation, its relation to continuous fermentation, and the cell recycling methods during cultivation. Finally, the prospects of semi-continuous fermentation technology were also discussed according to the recent progress on metabolic engineering and process optimization.

Key words: semi-continuous fermentation, research progress, application area, prospects

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