食品科学 ›› 2013, Vol. 34 ›› Issue (9): 364-368.doi: 10.7506/spkx1002-6630-201309072

• 专题论述 • 上一篇    下一篇

胰蛋白酶抑制剂的结构与功能研究进展

王荣春1,孙建华2,何述栋1,马 莺1,*   

  1. 1.哈尔滨工业大学食品科学与工程学院,黑龙江 哈尔滨 150090;
    2.黑龙江省科学院微生物研究所,黑龙江 哈尔滨 150010
  • 收稿日期:2013-03-11 修回日期:2013-04-20 出版日期:2013-05-15 发布日期:2013-05-07
  • 通讯作者: 马莺 E-mail:maying@hit.edu.cn

Recent Advance in Research on the Structure and Function of Trypsin Inhibitor

WANG Rong-chun1,SUN Jian-hua2,HE Shu-dong1,MA Ying1,*   

  1. 1. School of Food Science and Engineering, Harbin Institute of Technology, Harbin 150090, China;
    2. Institute of Microbiology, Heilongjiang Academy of Sciences, Harbin 150010, China
  • Received:2013-03-11 Revised:2013-04-20 Online:2013-05-15 Published:2013-05-07
  • Contact: MA Ying E-mail:maying@hit.edu.cn

摘要:

胰蛋白酶抑制剂属于丝氨酸蛋白酶抑制剂家族,其生理功能与防病虫害有关。近年来胰蛋白酶抑制剂因其独特的生理功能,如抗癌、抗病毒等,引起了广泛关注。本文对胰蛋白酶抑制剂的分类、典型的结构、功能及其提取和研究方法进行阐述,并对其应用潜力和存在的问题进行讨论,以期为胰蛋白酶抑制剂的进一步研究提供一定的参考。

关键词: 胰蛋白酶抑制剂, 蛋白结构, 功能, 应用

Abstract:

The physiological function of trypsin inhibitor, a member of the family of serine protease inhibitor, is associated
with preventing or combating diseases and insect pests. In recent years, trypsin inhibitor has attracted wide attention from
researchers because of its unique physiological properties such as anti-cancer and anti-virus activity. In this paper, we review
the classification, typical structure and functions of trypsin inhibitor. Besides, the application potential of some current
methods to extract and purify trypsin inhibitor and problems exisitng in their application are introduced, aiming at providing
references for further expolration of trypsin inhibitor.

Key words: trypsin inhibitor, protein structure, function, application

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