食品科学 ›› 2010, Vol. 31 ›› Issue (3): 250-252.doi: 10.7506/spkx1002-6300-201003058

• 营养卫生 • 上一篇    下一篇

蜂蛹富肽蛋白粉对大鼠免疫功能和血糖、血脂的影响

盛 晟,周 杰* ,沈咏舟,张 佳,朱枫桥   

  1. 安徽农业大学动物科技学院
  • 收稿日期:2009-04-07 出版日期:2010-02-01 发布日期:2010-12-29
  • 通讯作者: 周杰 E-mail:zhoujie@ahau.edu.cn
  • 基金资助:

    合肥市科技计划项目(合科[2007]15 号)

Effect of Honeybee Pupae Peptide-rich Protein Powder on Immune Function, Blood Glucose and Blood Lipid in Rats

SHENG Sheng,ZHOU Jie*,SHEN Yong-zhou,ZHANG Jia,ZHU Feng-qiao   

  1. College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China
  • Received:2009-04-07 Online:2010-02-01 Published:2010-12-29
  • Contact: ZHOU Jie E-mail:zhoujie@ahau.edu.cn

摘要:

选用50 只3 周龄SD 大鼠随机分成两组,分别灌喂蜂蛹蛋白粉和经消化酶水解的蜂蛹蛋白即富肽蛋白粉4周。结果表明,灌喂富肽蛋白粉可显著增加大鼠血清IgG、IgA 含量和脾脏指数(P < 0.05),对大鼠血清IgM 和胸腺指数的影响无统计学意义。灌喂富肽蛋白粉可极显著降低大鼠血糖(GLU)含量(P < 0.01),显著提高血清甘油三酯(TG)、血清高密度胆固醇(HDL-C)含量,降低血清低密度胆固醇(LDL-C)含量(P < 0.05),而对血清游离脂肪酸(FFA)和总胆固醇(TC)含量影响不显著。结果提示,富肽蛋白粉可增强大鼠的免疫功能、降低血糖,并能够预防和减轻动脉粥样硬化的发生。

关键词: 蜂蛹, 富肽蛋白粉, 大鼠, 免疫功能, 血糖, 血脂

Abstract:

Fifty 3-week-old SD rats were selected and randomly divided into 2 groups, namely treatment and control groups administered honeybee pupae peptide-rich protein powder and honeybee pupae protein powder for 4 consecutive weeks. Results showed that the contents of serum IgG, IgA and spleen index of rats treated with peptide-rich protein powder exhibited a significant increase (P<0.05), whereas no effect on serum IgM content and thymus index. In addition, compared with the control group, an extremely significant decrease in blood glucose (P < 0.01), a significant decrease in density lipoprotein cholesterol (LDL-C) content (P <0.05), and an increase in serum triglyceride (TG) content and density lipoprotein cholesterol (HDL-C) content (P < 0.05) were observed in rats treated with peptide-rich protein powder. However, peptide-rich protein powder had no significant effect on the contents of serum free fatty acids (FFA) and serum total cholesterol (TC). Therefore, peptide-rich protein powder can enhance immune function, decrease blood glucose, and prevent the occurrence of atherosclerosis.

Key words: honeybee pupae, peptide-rich protein powder, rat, immune function, blood glucose, blood lipid

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