食品科学 ›› 2010, Vol. 31 ›› Issue (2): 141-144.doi: 10.7506/spkx1002-6300-201002035

• 分析检测 • 上一篇    下一篇

桑椹药材HPLC 图谱研究

游元元1,万德光2,杨文宇3,裴瑾2   

  1. 1.成都医学院药学院 2.成都中医药大学药学院 3.西华大学生物工程学院
  • 收稿日期:2009-03-24 修回日期:2009-08-12 出版日期:2010-01-15 发布日期:2010-12-29
  • 通讯作者: 万德光2 E-mail:wdg@cdutcm.edu.cn
  • 基金资助:

    国家自然科学基金项目(30672625)

HPLC Profile Analysis of Fructus Mori

YOU Yuan-yuan1,WAN De-guang2,*,YANG Wen-yu3,PEI Jin2   

  1. (1. Pharmaceutical College, Chengdu Medical College, Chengdu 610083, China;
    2. Pharmaceutical College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China;
    3. College of Bioengineering, Xihua University, Chengdu 610039, China
  • Received:2009-03-24 Revised:2009-08-12 Online:2010-01-15 Published:2010-12-29
  • Contact: WAN De-guang2,*, E-mail:wdg@cdutcm.edu.cn

摘要:

目的:研究不同基源及产地桑椹药材的品质差异。方法:建立桑椹药材的HPLC 分析方法,比较不同样品的HPLC 图谱相似度,并进行聚类分析。结果:16 批桑椹样品相似程度不高,不同基源及产地样品的化学成分在组成与数量上存在差异,桑椹药材的品质与产地无明显相关性,杂交桑的桑椹总峰面积大于法定品种的桑椹总峰面积,市购商品药材品质差异大。结论:桑椹药材的品质与原植物种质、药材加工及贮存有较密切的关系。

关键词: 桑椹, 基源, 产地, HPLC, 聚类分析

Abstract:

Sixteen Fructus Mori samples of different origins and habitats were compared for quality difference according to their characteristic HPLC profiles and subjected to hierarchical cluster analysis. Besides, the optimal chromatographic conditions were discussed. A low similarity in HPLC profile and remarkable differences in content and chemical composition were observed among the 16 samples. There was no obvious correlation between quality and habitat of Fructus Mori. Samples from half-bred mulberry varieties displayed larger peak area than those stipulated in the Chinese pharmacopoeia. Commercial Fructus Mori products differed greatly in quality. All these results reveal that Fructus Mori quality is closely associated with mulberry variety, processing and storage.

Key words: Fructus Mori, origin, habitat, HPLC, hierarchical cluster analysis

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