食品科学 ›› 2009, Vol. 30 ›› Issue (5): 269-272.doi: 10.7506/spkx1002-6630-200905062

• 专题论述 • 上一篇    下一篇

壳聚糖衍生物抗菌活性研究进展

吴清平1,陈 威1,2,3,张菊梅1,吴慧清1   

  1. 1.广东省微生物研究所,广东省菌种保藏与应用重点实验室 2.中国科学院武汉病毒研究所 3.中国科学院研究生院
  • 收稿日期:2008-03-26 修回日期:2008-08-12 出版日期:2009-03-01 发布日期:2010-12-29
  • 通讯作者: 吴清平 E-mail:wuqp@gdas.ac.cn
  • 基金资助:

    广东省科技计划项目(2006A10601002)

Research Progress on Antibacterial Activity of Chitosan Derivatives

WU Qing-Ping1,CHEN Wei1,2,3,ZHANG Ju-mei1,WU Hui-qing1   

  1. (1.Guangdong Provincial Key Laboratory of Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou
    510070, China;2.Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China;
    3.Graduate University of Chinese Academy of Sciences, Beijing 100049, China)
  • Received:2008-03-26 Revised:2008-08-12 Online:2009-03-01 Published:2010-12-29
  • Contact: WU Qing-Ping1 E-mail:wuqp@gdas.ac.cn

摘要:

壳聚糖具有降低血液中胆固醇、降低血压、抗感染、控制关节炎、抗癌等多种作用。作为天然的食品防腐剂,壳聚糖不仅对人体无害,还具有很多保健作用。普通分子量的壳聚糖水溶性很差,一般使用酸溶液来溶解。通过合成各种壳聚糖的衍生物不仅提高了壳聚糖的水溶性还增强了它们的抗菌活性,使壳聚糖作为一种天然优质食品防腐剂成为可能。

关键词: 壳聚糖, 壳聚糖衍生物, 水溶性, 抗菌活性, 抗菌机理

Abstract:

Chitosan has many health functions such as decreasing blood cholesterol, lowering blood pressure, anti-infections, controlling arthritis, anti-cancer and so on. However, the water solubility of normal chitosan is very poor, which is usually dissolved with acid solution. Recently researchers found that synthesized chitosan derivatives not only can increase the water solubility of chitosan but also improve the antibacterial activity of chitosan, making it possible to use chitosan as a natural food preservative .

Key words: chitosan, chitosan derivative, water solubility, antibacterial activity, antibacterial mechanism

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