食品科学 ›› 0, Vol. ›› Issue (): 199-203.

• 基础研究 • 上一篇    下一篇

叶黄素-β-环糊精包合物的制备及其光谱研究

张多婷,韩 静*,项文娟,张 玥   

  1. 沈阳药科大学制药工程学院
  • 收稿日期:2010-10-13 修回日期:2011-08-26 出版日期:2011-09-15 发布日期:2011-08-30
  • 通讯作者: 韩静 E-mail:HJ-8080@163.com

Preparation and Spectral Studies of Lutein-β-cyclodextrin Inclusion

  • Received:2010-10-13 Revised:2011-08-26 Online:2011-09-15 Published:2011-08-30

摘要: 以β-环糊精(β-CD)为主体,超声法制备叶黄素-β-环糊精(叶黄素-β-CD)包合物,通过X射线粉末衍射光谱、红外光谱及差示扫描量热分析对叶黄素-β-CD包合物进行表征。结果表明:叶黄素-β-CD包合物的适宜包合条件为叶黄素与β-CD的物质的量比1:4,超声功率400W,超声时间40min,包合率可达到75.8%以上;产物的光谱特征的变化证实叶黄素和β-CD形成了新的物相;而用相溶解度确定叶黄素和β-CD的相溶解度曲线属于AL型,叶黄素与β-CD形成1:1包合物,包结常数为346.97L/mol。经包合后,叶黄素的稳定性与水溶性得到明显提高。

关键词: 叶黄素, β-环糊精, 包合物, 包结常数

Abstract: β-cyclodextrin was used as the host to prepare lutein-β-cyclodextrin inclusion by means of ultrasonic. The structure of lutein-β-cyclodextrin inclusion was characterized by Fourier transform infrared spectroscopy, differential scanning calorimetry, and X-ray diffraction spectroscopy. The results indicated that the optimal inclusion conditions were lutein-to-β-cyclodextrin ratio of 1:1, ultrasonic power of 400 W, and ultrasonic treatment time of 40 min. Under the optimal inclusion conditions, the yield of lutein-β-cyclodextrin was 75.8%. The spectral characteristics of the product revealed that lutein and β-cyclodextrin could form inclusion with a ratio of 1:1 and the inclusion constant was 346.97 L/mol. The stability and water solubility of lutein was significantly increased through the inclusion reaction.

Key words: lutein, β-cyclodextrin, inclusion compound, inclusion constant