食品科学 ›› 2006, Vol. 27 ›› Issue (3): 216-218.

• 营养卫生 • 上一篇    下一篇

复方山楂黄酮的提取及调脂研究

 李久长, 马挺军, 刘诚   

  1. 山西大学生命科学与技术学院; 北京农学院食品科学系; 北京食品研究所
  • 出版日期:2006-03-15 发布日期:2011-09-06

Studies on Optimum Extraction Process of Flavonoids from Hawthorn and Their Adjustment to Hyperlipidemia

LI  Jiu-Chang, MA  Ting-Jun, LIU  Cheng   

  1. 1.College of Life Science and Technology, Shanxi University, Taiyuan, 030006, China;2.Department of Food Science, Beijing Agricultural College , Beijing 102206, China;3.Beijing Food Research Institute, Beijing 100076, China
  • Online:2006-03-15 Published:2011-09-06

摘要:  本文通过正交试验及方差分析确定了复方山楂中提取黄酮的最佳工艺条件,即:70%乙醇、70℃、pH5.5~6.4下冷凝回流2h,再用乙酸乙酯萃取,黄酮浸出率为2.2%。研究了复方山楂提取物对大鼠血清TC、TG、HDL-C的影响。在治疗组中复方山楂提取物具有抑制高血脂大鼠的作用,具有较好的调脂功能,与脂必妥片的调脂效果相同。

关键词: 复方山楂提取物, 黄酮, 高血脂模型, TC, TG, HDL-C

Abstract: The methods of hawthorn flavanoids extraction were studied. The results showed that the optimum conditions were :soaking solution 80% ethanol, temperature 80℃, the ratio of soild-to-liquid 1:10 and time 4 h. The extraction rate of flavonoidswas as high as 2.2%. It could reduce the hyperlipidemia of wistar TC and TG, also distinctly raise the HDL-C level. Soakingflavonoids of hawthorn could better adjust hyperlipidemia, and have the same effect as ZHIBITUO tablets.

Key words: the soaked things of compound hawthorn, flavonoids, the model of hyperlipidemia, TC, TG, HDL-C