食品科学 ›› 2005, Vol. 26 ›› Issue (5): 165-167.

• 工艺技术 • 上一篇    下一篇

香料2-甲基四氢呋喃-3-酮的合成研究

 刘晓庚, 陈优生   

  1. 南京财经大学应用化学系,广东化工制药职业技术学院
  • 出版日期:2005-05-15 发布日期:2011-09-19

Study on Synthesis of 2-Methyltetrafuran-3-one from Ethyl Lactate and Methyl Acrylate

 LIU  Xiao-Geng, CHEN  You-Sheng   

  1. 1.Applied Chemical Department, Nanjing University of Finance and Economics, Key Lab of Cereal and Oil’s By- products Utilization in Jiangsu Province;2.Guangdong Vocational and Technical Institute of Chemical Engineering Pharmaceutics
  • Online:2005-05-15 Published:2011-09-19

摘要: 以乳酸乙酯与丙烯酸甲酯为主要原料用相转移催化法在室温离子液体中经过缩合和酸性水解合成制得2-甲基-4-甲酯四氢呋喃-3-酮。对此方法的工艺条件用正交试验法进行了优化,并提出了两步合成法的反应机理。在最佳条件的合成收率为74.4%以上;并对合成产物进行IR、NMR和理化性质的测定,结果表明所合成的物质与标准品的数据一致。

关键词: 2-甲基-4-甲酯四氢呋喃-3-酮, 合成, 相转移催化, 微波辐照

Abstract: 2-methyltetrafuran-3-one is a by the condensation and acid hydrolysis of ethyl lactate and methyl acrylate by way of PTC (phase transfer catalysis) in ionic liquid at room temperature. The technology is optimized by orthongonal test. The yield is above 74.4% after optimization. The product meet standard material after the comparison of their IR, UV, NMR and properties.

Key words: 2-methyltetrafuran-3-one, synthesis, phase transfer catalysis, microwave irradiation