食品科学 ›› 2005, Vol. 26 ›› Issue (6): 246-248.

• 营养卫生 • 上一篇    下一篇

茶树菇多糖对荷瘤动物模型影响的研究

 徐静娟, 邬敏辰, 陈屏   

  1. 江南大学医学系
  • 出版日期:2005-06-15 发布日期:2011-09-19

The Influence of Agrocybe aegerita Polysaccharides(AAP) on Bearing Tumor Animal Model

 XU  Jing-Juan, WU  Min-Chen, CHEN  Ping   

  1. Department of Medicien, Southern Yangtze University
  • Online:2005-06-15 Published:2011-09-19

摘要: 对茶树菇多糖对荷瘤动物模型的影响进行了研究,实验结果表明:茶树菇多糖对小鼠S180移植肉瘤及S180腹水瘤具有显著的抑制作用,对环磷酰胺所致的实验小鼠白细胞数下降有显著的升高作用。

关键词: 茶树菇多糖, S180移植性肿瘤, 抑瘤作用

Abstract: Purpose:Study the effect of AAP on mouse with tumor and the resistant effect on depression of the number of WBC (White blood cell) caused by CP(cyclophsphamide). Methods: Select the targets such as inhibitory rate of tumor, cell division index, survival time and the number of WBC to evaluate the influence of different concentrations of AAP on S 180 ascites sarcoma and transplantation sarcoma in mouse. Results: Comparing with the control, the AAP can inhibit the mouse’s sarcoma from growing, prolong the survival time of mouse bearing tumor and increase the numbers of WBC depressed caused by CP. Conclusion: AAP has antineoplastic effect, it’s may be related to its immunity regulation.

Key words: Agrocgbe aegerita polysaccharides, S180 ascites sarcoma, inhibit sarcoma