食品科学 ›› 2005, Vol. 26 ›› Issue (9): 320-322.

• 工艺技术 • 上一篇    下一篇

维生素E琥珀酸酯精细分离的研究

 伍林, 王艳, 鲁亮, 秦晓蓉, 易德莲   

  1. 武汉科技大学应用化学研究所
  • 出版日期:2005-09-15 发布日期:2011-09-20

Study on Fine Separation of Vitamin E Succinate

 WU  Lin, WANG  Yan, LU  Liang, QIN  Xiao-Rong, YI  De-Lian   

  1. Applied Chemistry Research Institute, Wuhan University of Science and Technology
  • Online:2005-09-15 Published:2011-09-20

摘要: 维生素E琥珀酸酯(VES)较维生素E(VE)的性质稳定,在医药和化妆品等领域得到了更广泛的应用。以维生素E和琥珀酸酐为原料,丙酮为溶剂,三乙胺为催化剂反应得到了维生素E琥珀酸酯的反应液。将反应液在3℃下冷却静置10h左右,琥珀酸酐沉淀析出,回收率82.6%:0.08MPa下减压蒸馏出三乙胺和丙酮;蒸镏余液用止己烷溶解,溶液很快沉淀分层,经过滤、洗涤得到VES,回收率为82%,纯度为93%。

关键词: 维生素E, 维生素E琥珀酸酯, 琥珀酸酐, 三乙胺, 分离

Abstract: Compared with vitamin E (VE), vitamin E succinate (VES) is stabler and has a wide use in medical and cosmetics fields. The reaction solution was prepared by vitamin E and succinic anhydride as resource, acetone as solvent, triethylamine as catalyst. The reaction solution was placed at 3FFC for about ten hours and the succinic anhydride can be cemented out from the mixture, the reclaiming can reach 82.6%. Then the distillation cut of triethylamine and acetone were got in the vacuum of 0.08MPa. The residue was dissolved in hexane. The solution precipitated and separated quickly, then it was filtrated and washed; the reclaiming of VES is 82% and purity of the product is 93%.

Key words: VE: vitamin E succinate, succinic anhydride: triethylamine, separation