食品科学 ›› 2005, Vol. 26 ›› Issue (10): 216-219.

• 营养卫生 • 上一篇    下一篇

恒顺香醋对人低密度脂蛋白(LDL)氧化修饰的影响

 徐清萍, 陶文沂, 敖宗华   

  1. 江南大学工业生物技术教育部重点实验室
  • 出版日期:2005-10-15 发布日期:2011-09-25

Effect of Hengshun Aromatic Vinegar on Oxidative Modification of Low Density Lipoprotein(LDL)

 XU  Qing-Ping, TAO  Wen-Yi, AO  Zong-Hua   

  1. The Key Laboratory of Industrial Biotechnology, Ministry of Education, Southern Yangtze University
  • Online:2005-10-15 Published:2011-09-25

摘要: 本文研究了恒顺香醋浓缩物(HV),恒顺香醋提取物(HVE)及其各不同分子量组分(HF1、HF2、HF3、HF4)对低密度脂蛋白氧化修饰(LDL)的影响,并研究了恒顺香醋浓缩物对已受到氧化修饰的LDL的影响。在加入Cu2+与LDL一起温浴前,添加HV、HVE及HVE各分离组分均能够抑制丙二醛的产生。LDL与Cu2+一起温浴2h,然后添加HV,添加组与对照组相比,丙二醛的产生量有明显差别。结果表明恒顺香醋浓缩物(HV),恒顺香醋提取物(HVE)及其各不同分子量组分(HF1、HF2、HF3、HF4)能抑制人低密度脂蛋白氧化修饰,且HV对已受到氧化修饰的LDL的氧化有一定的阻断作用。

关键词: 恒顺香醋, 低密度脂蛋白, 氧化修饰, Cu2+

Abstract: In this paper the effect of Hengshun aromatic vinegar condensed (HV), Hengshun aromatic vinegar extract (HVE)and individual Hengshun aromatic vinegar fractions (HF1, HF2, HF3, HF4) on oxidative modification of low density lipoprotein (LDL) were studied. In addition, effect of HV on oxidatively modified LDL was studied. Before the incubation of LDL with Cu2+, addition of HV, HVE and individual Hengshun aromatic vinegar fractions to the culture could suppress the generation of MDA. LDL was incubated with Cu2+ for 2h, then HV was added to the culture, there were significant differences in MDA content between the groups of addition and control (without HV). The results showed that HV, HVE and individual Hengshun aromatic vinegar fractions could inhibit the oxidative modification of LDL, and HV could block the oxidative reaction of the already oxidatively modified LDL.

Key words: Hengshun aromatic vinegar, low density lipoprotein, oxidative modification, Cu2+