食品科学 ›› 2003, Vol. 24 ›› Issue (12): 112-115.

• 营养卫生 • 上一篇    下一篇

华南野生蔬菜白仔菜的毒理学研究

 郭巨先, 杨暹   

  1. 华南农业大学园艺学院
  • 出版日期:2003-12-15 发布日期:2011-12-13

Toxicology Studies on Gynura divaricata in the South China Wild Vegetable

 GUO  Ju-Xian, YANG  Xian   

  1. College of Horticulture, South China Agricultural University
  • Online:2003-12-15 Published:2011-12-13

摘要: 本实验以华南野生蔬菜白仔菜为材料,对其毒理学进行了较全面的科学评价。结果表明:小鼠经口服LD50>10000mg/kg•bw,属于急性无毒范围;白仔菜引起小白鼠的精子畸形率增多;白仔菜30d喂养对SD大白鼠的生长影响不明显,但中、高剂量喂养可引起大白鼠的血液生化指标ALP的升高和BUN、CREA的降低,病理检测表明高剂量的喂养导致大鼠脾、肝、肾脏等器官的损害,说明白仔菜可能具有蓄积毒性。

关键词: 华南, 野生蔬菜, 白仔菜, 毒理学

Abstract: A comprehensive and scientific evaluation had been made on the toxicity of Gynura divaricata in South China. Theresults were shown as follows: During 7 days period of observation after a treatment with a LD50>10000mg/kg•bw bymouth, The G. divaricata caused an increase of sperm abnormality in mice. The 30 days feeding with G. divaricata had no obviousinfluence on the growth of the mice, but the medium and high dose feeding could cause an increase of ALP, and a decrease of BUNand CREA in the mice. Pathological detection indicated that high-dose feeding resulted in damage to spleen, liver, kidney etc. Inthe animal tests, it proved that G. divaricata might have an accumulative toxicity.

Key words: south China, wild vegetable, Gynura.divaricata, toxicology