食品科学 ›› 2003, Vol. 24 ›› Issue (4): 136-138.

• 营养卫生 • 上一篇    下一篇

低聚果糖对小鼠肠道菌群、血甘油三酯及血尿素氮的影响

 罗予, 蔡访勤, 孟林敏, 赵国新   

  1. 河南省医学科学研究所
  • 出版日期:2003-04-15 发布日期:2011-12-13

Effect of Fructooligosaccharide on the Intestinal Flora, Serum Triglyceride an d Blood Urea Nitrogen in Mice

 LUO  Yu, CAI  Fang-Qin, MENG  Lin-Min, ZHAO  Guo-Xin   

  • Online:2003-04-15 Published:2011-12-13

摘要: 目的观察低聚果糖(FOS)对小鼠肠道菌群、血甘油三酯(Tg)及血尿素氮(BUN)的影响。方法FOS0.1g/kg和1g/kg•bw•d.分组ig(灌服)小鼠连续14d后,取粪便,滴种选择性培养基,孵育,平板菌落计数法测菌群,酶法(GPO-PAP)测Tg,37℃-OPA法测BUN。结果和正常对照组相比,ig1g/kg的小鼠肠道双歧杆菌和肠杆菌数量增加(p<0.05);BUN含量上升(p<0.01)、Tg含量下降;ig0.1g/kg的小鼠BUN和Tg含量均上升(p<0.05),肠道类杆菌数量减少。结论FOS1g/kg•bw•d×14d的用量,可增殖肠道双歧杆菌和肠杆菌,降低血Tg含量,而0.1g/kg•bw•d×14d用量即可使BUN含量上升。

关键词: 低聚果糖, 肠道菌群, 甘油三酯, 血尿素氮

Abstract: Objective:To study the effects of fructooligosaccharide (FOS) on i nt estinal flora,serum triglyceride (Tg) and blood urea nitrogen (BUN). Methods: T he mice were fed FOS (0.1g/kg and 1g/kg• bw•d respectively) for 14d. The feac al flora,Tg and BUN were assayed respectively. Results: In 1/kg group,the co u nts of Bifidobacterum and Enterobacteriaceae and the BUN were increased than t he control group. In 0.1g/kg group,the BUN and Tg were increased (p< 0.05),t he counts of Bacteroides were decreased,than the control group. Conclusion: Th e FO S of 1 g/kg•bw•d×14d can increase the counts of intestinal Bifidobacteri um an d Enterobacteriaceae,and can decrease serium Tg. The FOS of 0.1 g/kg and 1 g/kg •bw•d×14d can increase BUN.

Key words: fructooligosaccharide, intestinal flora, triglyceride, blood urea n itrogen