食品科学 ›› 2003, Vol. 24 ›› Issue (4): 133-136.

• 营养卫生 • 上一篇    下一篇

番茄红素对非特异性免疫功能的体外实验研究

 袁暾, 魏大鹏, 廖林川, 王霞, 蔡美英   

  1. 四川大学基础和法医学院免疫教研室
  • 出版日期:2003-04-15 发布日期:2011-12-13

In Vitro Study on Assaying Lycopene with Non-specific Immunity

 YUAN  Tun, WEI  Da-Peng, LIAO  Lin-Chuan, WANG  Xia, CAI  Mei-Ying   

  • Online:2003-04-15 Published:2011-12-13

摘要: 在细胞培养条件下,观察了番茄红素对机体非特异性免疫的影响。结果发现适宜浓度番茄红素乙醇溶液对T淋巴细胞转化有促进作用(p<0.01)。适当浓度的番茄红素对NK细胞杀伤功能也有一定的促进作用(p<0.05)。说明番茄红素对非特异性细胞免疫的主要指标有明确的促进。其原因可能是保护了T淋巴细胞的DNA,避免了增殖过程中DNA复制时可能发生的损伤。番茄红素可以促进细胞胞间通信最终也表现为T淋巴细胞功能的促进。

关键词: 番茄红素, 细胞培养, 非特异性免疫, 氧自由基

Abstract: Lycopene with non-specific immunity was studied in cell culture co nd ition. The results indicated that lycopene ethanol solution increased the abilit y of T lymphocytes to proliferate following the stimulation in proper concentra t ion (p< 0.01).In proper concentration, the lycopene ethanol solution could pro mo te the killing ability of NK cells(p< 0.05).So, lycopene swelled the non-spe cif ic immunity improved. The reason might be the DNA protecting of T lymphocyty and the increasing intercellular communication.

Key words: lycopene, cell culture, non-specific immunity, oxygen-derived fre e radidicals