食品科学 ›› 2007, Vol. 28 ›› Issue (4): 302-305.

• 营养卫生 • 上一篇    下一篇

蜜环菌壳聚糖对果蝇寿命和D-半乳糖致衰老小鼠的影响

 丁诚实, 沈业寿, 彭世奇   

  1. 安徽大学生命科学学院糖复合物与糖工程实验室; 安徽大学生命科学学院糖复合物与糖工程实验室 安徽 合肥 230039; 安徽 合肥 230039;
  • 出版日期:2007-04-15 发布日期:2011-12-31

Effects of AMC on Lifespan of Drosophila melanogaster and D-galactose-induced Mice Aging

 DING  Cheng-Shi, SHEN  Ye-Shou, PENG  Shi-Qi   

  1. Laboratory of Glycoconjugates and Glycotechnology,School of Life Science,Anhui University,Hcfei 230039,China
  • Online:2007-04-15 Published:2011-12-31

摘要: 提取蜜环菌壳聚糖(AMC)并分析其理化性质;观察AMC对果蝇寿命和D-半乳糖致衰老小鼠的影响,分析小鼠学习记忆行为、血清中SOD的活性、MDA的含量及胸腺系数和脾脏系数的变化情况。结果得到的AMC,含量为95%,脱乙酰度92%,粘均分子量为85000,其具有显著的抗衰老作用。

关键词: 蜜环菌, 壳聚糖, 提取, 理化性质, 衰老

Abstract: The chitosan was isolated from Armillariella mellea(AMC),and its relevant physical and chemical properties were analysed.The effects of chitosan from Arillariella mellea(AMC)on the lifespan of Drosophila melanogaster and D-galactose. induced mice aging were observed,and also the ability of learning and memory,the activities of SOD,the levels of MDA in serum,the thymus index and the spleen index were assayed.Results showed that the purity of such chitosan is 95%,the degree of deacetylation is 92%,and the viscosity average molecular weight is 85000.The AMC has remarkable anti-aging effects.

Key words: Armillariella mellea, chitosan, isolation, physical and chemical property, aging