食品科学 ›› 2002, Vol. 23 ›› Issue (7): 139-141.

• 专题论述 • 上一篇    下一篇

红曲霉产桔霉素的研究动态

 赖卫华, 许杨   

  1. 南昌大学生命科学与食品工程学院,中德联合研究院
  • 出版日期:2002-07-15 发布日期:2011-12-31

Tendency of Research on Monascus Pro ducing Citrini

 LAI  Wei-Hua, XU  Yang   

  • Online:2002-07-15 Published:2011-12-31

摘要: 红曲霉在食物中的应用已有千年的历史。近年来,由于它能够生成多种生理活性物质而备受各国的关注。然而,目前发现多种长期应用于工业生产的红曲霉在产生色素和生理活性物质的同时,还能分泌一种真菌毒素—桔霉素。桔霉素主要作用的靶器官是肾脏,它不仅可以致畸、导致肿瘤的发生,而且可以诱发突变。本文综述了近年来有关红曲霉产桔霉素的研究动态,其中包括桔霉素的理化性质、毒性、检测方法、桔霉素在红曲霉培养过程中的动力学研究以及抑制其生成的对策。

关键词: 红曲霉, 桔霉素, 动态

Abstract: Monascus has beenusedtopreparered moldriceas anaturalfoodpigments andalsoas afooddisinfectantfor a thousand years.The physiologically active substance produced by mnascus has been researched widely.At pr esent,however,most of monascus,widely usedin industry,were proved to produce citrinin,which is a mycotoxin,accompa-nying with pigments and physiologic ally active substance,Kidney is the target organ of citrinin,resulting in not only teratogenicity and carcinogenicity but also mutagenicity.This review set forth the recent tendency of stud y about cit-rinin,including the physical andch emical properties,the toxicologic al characteristics,the detection m ethods and the kinetic analysis of red pigment and c itrinin production by monascus.Hen ce the method was suggested to inhibi t the ex-cretion of citrinin.

Key words: Monascus , Citrinin , Tendency