食品科学 ›› 2002, Vol. 23 ›› Issue (7): 95-97.

• 营养卫生 • 上一篇    下一篇

玉米胚延缓衰老作用的研究

 董文彦, 马熙媛, 张东平, 于少梅   

  1. 北京联合大学应用文理学院生化系
  • 出版日期:2002-07-15 发布日期:2011-12-31

Effect of Maize Embryo on Delaying Aging

 DONG  Wen-Yan, MA  Xi-Yuan, ZHANG  Dong-Ping, YU  Shao-Mei   

  • Online:2002-07-15 Published:2011-12-31

摘要: 研究玉米胚的延缓衰老作用:方法:用高脂饲料造成鼠类衰老模型,实验组在高脂饲料中加入15%或20%的玉米胚,分别用雌、雄性瑞士小鼠进行45或50d的喂养实验,测定红细胞超氧化物歧化酶(SOD)、血清过氧化脂质(LPO)、谷胱甘肽过氧化物酶(GSH-Px)以及高密度脂蛋白胆固醇(HDL-C)、尿酸和皮肤羟脯氨酸(Hyr)等生化指标。结果:实验组与模型组比较,不论雌、雄性小鼠SOD、GSH-Px活性明显提高(P<0.05),LPO含水量显著降低(P<0.05),雄性小鼠的HDL-C及皮肤羟脯氨酶(Hyr)含量升高显著(p<0.05),而尿酸的含量则下降35.6%(P<0.01)结论:玉米胚具有显著的抗氧化作用。能够延缓衰老。

关键词: 玉米胚, 过氧化脂质, 超氧化物歧化酶, 谷胱甘肽过氧化物酶高密度脂蛋白胆固醇, 尿酸

Abstract: Objective:To investigate the effect of maize embryo on delaying aging.M ethods:An animal model of aging wasestablishedbytreatingSwissmi cewithhighlipidsfeed.Thefoodwhi chcontained15%or20%maizeembryopowder was fed to female and male mice in the e xperimental group for 45or 50days.T he projects of biochemical assay about delayingagingcompoundsfromblood tissuewerecarriedoutResults:Inc omparisonwithmodelgrouptheconte ntofilpid peroxides(LPO)in serumwas reduced(P<0.01),the activity of superoxide dismuta se(SOD)in red bloodcells was singnificantly in creased(P <0.05),the activity of glutathhionperoxidase(GSH -Px)was increased(p <0.01or p<0.05),thecontentofhydroxyprolin(Hyp)inskinwas lift(p <0.01),thecontentofHDL -Cinserumwas obviously increased(p <0.05),andthe content of uric acidin serum was lowed(p <0.01)Conclution:These results indicate d thatmaizeembryohadamarkedanti -o xidationeffectlandthereforeeffe ctondelayingaging.Hencemaizemeb ryois a kindof newnatural resources of the health food.

Key words: Maize embryo , Lipid peroxides , Supero xide , Dismutase , Glutathion peroxidase , High den-sity lipoprotein cholesterol , Uric a cid