酶解骨钙粉细粉与普通酶解骨钙粉增加骨密度功能比较

食品科学 ›› 2012, Vol. 33 ›› Issue (21): 303-307.

酶解骨钙粉细粉与普通酶解骨钙粉增加骨密度功能比较

周倩1，马丹丹1，李梦洁1，朱文丽1,*，王娜2 ，张葳芮2

1.北京大学医学部公共卫生学院营养与食品卫生学系 2.天津市天狮生命科学与技术研究院

收稿日期:2011-09-23 修回日期:2012-09-01 出版日期:2012-11-15 发布日期:2012-11-09
通讯作者: 朱文丽 E-mail:zhuwenli@bjmu.edu.cn

A Comparative Study of the Improving Effects of Enzymatic Bone Fine Powder and Enzymatic Bone Ordinary Powder on Bone Density in Rats

Wen-Li ZHU¹,

Received:2011-09-23 Revised:2012-09-01 Online:2012-11-15 Published:2012-11-09
Contact: Wen-Li ZHU E-mail:zhuwenli@bjmu.edu.cn

摘要/Abstract

摘要： 目的：分析比较酶解骨钙粉细粉与普通酶解骨钙粉增加大鼠骨密度功能和对钙吸收率的影响。方法：SPF级4周龄雌性SD大鼠100只，随机分为10组，即酶解骨钙粉细粉和普通酶解骨钙粉低、中、高剂量组，相应剂量碳酸钙对照组(低、中、高剂量组饲料钙含量分别为216.7、283.3、550.0mg/100g)，以及低钙对照组(饲料钙含量为150mg/100g)。喂养13周，检测钙表观吸收率、骨钙含量、骨密度、骨长和骨恒质量。结果：酶解骨钙粉细粉组股骨骨密度明显高于低钙对照组且不低于相应剂量碳酸钙对照组(P＞0.05)；普通酶解骨钙粉组股骨三点骨密度均明显高于低钙对照组，但低剂量组股骨钙含量和远心端股骨密度均低于碳酸钙对照组(P＜0.05)。酶解骨钙粉细粉和普通酶解骨钙粉相应剂量组的钙表观吸收率、骨钙含量、骨密度、骨长、总食物利用率和喂养13周时的体质量均无明显差异(P＞0.05)；酶解骨钙粉细粉中剂量组骨恒质量高于普通酶解骨钙粉中剂量组(P＜0.05)。结论：酶解骨钙粉细粉具有增加骨密度的作用，不能判定普通酶解骨钙粉具有增加骨密度的作用。酶解骨钙粉细粉在增加骨密度功能方面优于普通酶解骨钙粉。

关键词: 酶解骨钙粉细粉, 普通酶解骨钙粉, 骨密度, 钙表观吸收率

Abstract: Objective: To compare the improving effects of enzymatic bone fine powder (EBFP) and enzymatic bone ordinary powder (EBOP) on bone density and apparent calcium absorption rate (ACAR) in rats. Methods: Totally 100 female SD rats at 4 weeks old were randomly divided into 10 groups of 10 rats each including high-, medium- and low-dosage EBFP and EBOP groups, high-, medium- and low-dosage calcium carbonate (CC) groups (550.0, 283.3 mg and 216.7 mg of calcium in per 100 g of feed, respectively), and low calcium (LC) control group (150 mg of calcium in per 100 g of feed). After 13 weeks of feeding, ACAR, bone calcium content, bone density, bone length and bone constant weight in rats were determined. Results: Femur bone density in EBFP groups was significantly higher than that in LC group (P＞0.05), but was not lower than that in the CC control groups. Femur bone density in EBOP groups was significantly higher than that in LC group, but femur bone calcium content and distal femoral bone mineral density were lower in low-dosage EBOP group than CC group (P＜0.05). There was no significant difference (P＞0.05) in ACAR, bone calcium content, bone density, bone length, total food utilization and body weight between EBFP and EBOP groups at the same dosage. Femur bone constant weight was higher in medium-dosage EBFP group than medium-dosage EBOP group (P＜0.05). Conclusion: Enzymatic bone fine powder can increase bone density in rats, while it is uncertain whether enzymatic bone ordinary powder can do so.

Key words: enzymatic bone fine powder, enzymatic bone ordinary powder, bone mineral density (BMD), apparent calcium absorption rate

中图分类号:

Q593.6 R151.2

周?倩1，马丹丹1，李梦洁1，朱文丽1,*，王?娜2?，张葳芮2 . 酶解骨钙粉细粉与普通酶解骨钙粉增加骨密度功能比较[J]. 食品科学, 2012, 33(21): 303-307.

Wen-Li ZHU. A Comparative Study of the Improving Effects of Enzymatic Bone Fine Powder and Enzymatic Bone Ordinary Powder on Bone Density in Rats[J]. FOOD SCIENCE, 2012, 33(21): 303-307.

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