重离子束-紫外线复合诱变选育高产Lovastatin土曲霉菌株

食品科学 ›› 2013, Vol. 34 ›› Issue (3): 158-162.

重离子束-紫外线复合诱变选育高产Lovastatin土曲霉菌株

宋红平,李师翁

兰州交通大学化学与生物工程学院

收稿日期:2011-10-13 修回日期:2013-01-05 出版日期:2013-02-15 发布日期:2017-12-29
通讯作者: 李师翁 E-mail:lishweng@mail.lzjtu.cn
基金资助:
国家自然科学基金

Screening of a high lovastatin-producing Aspergillus terreus mutant by UV combined with heavy-ion beams irradiation

Received:2011-10-13 Revised:2013-01-05 Online:2013-02-15 Published:2017-12-29

摘要/Abstract

摘要： 利用重离子束与紫外线复合诱变的方法，选育得到一株高产Lovastatin土曲霉菌株Aspergillus terreus UV150-3。液态摇瓶发酵中Lovastatin产量达966.3 ug/mL，较原始出发菌株A. terreus CA99提高了5.6倍。经连续传代5培养，其遗传性状均比较稳定。

中图分类号:

TQ464.9

宋红平李师翁. 重离子束-紫外线复合诱变选育高产Lovastatin土曲霉菌株[J]. 食品科学, 2013, 34(3): 158-162.

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