Abstract: N-propanol was used to extract tea saponin from the oil tea (Camellia oleifera Abel) seed meal. Impact of the mesh of material particles, the concentration of n-propanol, solid-liquid ratio, extraction time, extraction temperature and the pH of extract on the extraction effect was examined, and the optimal process was obtained by orthogonal experiment. To the tea saponin yield for the target, the best extraction conditions were oil tea seed meal of 60 mesh, n-propanol concentration of 80%, solid-to-liquid ratio of 1:12, extraction temperature of 80℃ and extraction time of 3hours. Under these conditions, the tea saponin yield was 20.13%, and the purity was 62.78%. To the purity of tea saponin for the target, the best extraction conditions were n-propanol concentration of 90%, extraction temperature of 80℃, oil tea seed meal of 40 mesh, extraction time of 3hour, solid-to-liquid ratio of 1:11. Under these conditions, the purity of tea saponin was 72.06%, the yield 15.31%. The yield and purity of tea saponin derived from this process were superior to the conventional ethanol extraction.