食品科学 ›› 2013, Vol. 34 ›› Issue (11): 321-326.doi: 10.7506/spkx1002-6630-201311068

• 专题论述 • 上一篇    下一篇

源于果蔬的黄酮类化合物及其抗肿瘤作用靶点研究进展

任 虹1,张乃元2,田文静1,张 瑞1,胡仁杰1   

  1. 1.北京工商大学食品学院,食品添加剂与配料北京高校工程研究中心,北京市食品风味化学重点实验室,北京 100048;
    2.武汉大学公共卫生学院,湖北 武汉 430071
  • 收稿日期:2012-03-13 修回日期:2013-05-03 出版日期:2013-06-15 发布日期:2013-06-03
  • 通讯作者: 任虹 E-mail:renhong@th.btbu.edu.cn
  • 基金资助:

    国家高技术研究发展计划(863计划)课题

Research Advance in Flavonoids Derived from Fruits and Vegetables and Corresponding Molecular Targets of Anticancer

REN Hong1,ZHANG Nai-yuan2,TIAN Wen-jing1,ZHANG Rui1,HU Ren-jie1   

  1. 1. Beijing Higher Institution Engineering Research Center of Food Additives and Ingredients, Beijing Key Laboratory of Flavor
    Chemistry, School of Food and Chemical Engineering, Beijing Technology and Business University, Beijing 100048, China;
    2. School of Public Health, Wuhan University, Wuhan 430071, China
  • Received:2012-03-13 Revised:2013-05-03 Online:2013-06-15 Published:2013-06-03
  • Contact: REN Hong E-mail:renhong@th.btbu.edu.cn

摘要:

黄酮类化合物(flavonoids)广泛存在于各种水果、蔬菜中,具有种类繁多、结构复杂、药理活性强、毒副作用低的特点,富含黄酮类化合物的果蔬饮食可有效降低恶性肿瘤的患病率,对于恶性肿瘤的预防和治疗具有广泛意义。本文按化合物结构综述源于果蔬的黄酮类化合物及其抗肿瘤作用靶点的研究进展,为进一步开拓其食疗价值提供科学依据。

Abstract:

Flavonoids are existed widely in various fruits and vegetables with the characteristics of large amount, complex
structure, obvious pharmacological activity and low toxicity. A diet rich in flavonoids can be associated with the reduced risk for
cancers, which has important significance on prevention and treatment of malignant tumors. In this paper, the studies on flavonoids
derived from fruits and vegetables as well as their anticancer activity and corresponding molecular targets in terms of their chemical
structures are summarized, which will provide a scientific basis for further developing their therapeutic value of diets.

Key words: fruits and vegetables, flavonoids, anticancer activity, molecular targets

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