食品科学 ›› 2013, Vol. 34 ›› Issue (3): 267-270.

• 专家约稿 • 上一篇    下一篇

不同处理条件小黑豆乳清蛋白的抗肿瘤作用

王菲1,王常青2,樊迎1,于书佳1,原敏1,连伟帅1   

  1. 1. 山西大学生命科学学院
    2. 山西大学
  • 收稿日期:2012-03-01 修回日期:2013-01-13 出版日期:2013-02-15 发布日期:2017-12-29
  • 通讯作者: 王常青 E-mail:wcq@sxu.edu.cn
  • 基金资助:
    山西省科技攻关计划

Study on Anti-tumor Activity of Whey Protein Treated at Different Tempreture from Small Black Soybean

  • Received:2012-03-01 Revised:2013-01-13 Online:2013-02-15 Published:2017-12-29

摘要: 研究不同温度处理的小黑豆乳清蛋白对S180动物模型的影响。试验结果表明,经75℃处理的小黑豆乳清蛋白在3g/kg和10g/kg摄入剂量时,没有致胰腺肿大作用,对S180肿瘤的抑制效果优于65℃处理组,且瘤重比显著低于65℃处理组(P<0.05)。75℃小黑豆乳清蛋白组的胸腺指数较其它各组明显提高(P<0.05),与基础组处于同一水平。与模型组相比,75℃处理组动物的白细胞数、肿胀度和半数溶血值极显著升高(P<0.01),且显著高于65℃处理组(P<0.05)。提示小黑豆乳清蛋白经过75℃处理后能显著提高抗S180肿瘤的能力。

Abstract: In this paper, the effect of small black soybean whey protein, which was treated at different tempreture, on S180 animal model was studied. The results indicated that there was no tumefaction of the pancreas of 75℃ treated whey protein at 3 g/kg and 10 g/kg intake doses, and the inhibition effect on S180 tumor and tumor index of whey protein treated at 75℃ were better than 65℃(P<0.05) significantly. The thymus index of mice in 75℃whey protein group,which was at the same level as the basic group ,was significantly higher than those of mice in other groups(P<0.05). The white blood cell, the ear swelling degree and HC50 of mice in 75℃ whey protein group were significantly higher than those of mice in the model group(P<0.01) and the 65℃ whey protein group (P<0.01).Therefore, the antitumor ability on S180 tumor can be significantly improved by small black soybean whey protein treated at 75℃.

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