酶法制备人乳脂替代品的研究进展

食品科学 ›› 2013, Vol. 34 ›› Issue (3): 298-302.

酶法制备人乳脂替代品的研究进展

张超越¹,辛嘉英²,王艳¹,陈林林²

1. 哈尔滨商业大学食品工程学院
2. 哈尔滨商业大学

收稿日期:2012-03-31 修回日期:2013-01-09 出版日期:2013-02-15 发布日期:2017-12-29
通讯作者: 辛嘉英 E-mail:xinjiaying@yahoo.com.cn
基金资助:
黑龙江省杰出青年基金项目;黑龙江省教育厅科技创新团队计划项目;黑龙江省研究生创新科研资金

Advances in Enzymatic Production of Human Milk Fat Substitutes

Received:2012-03-31 Revised:2013-01-09 Online:2013-02-15 Published:2017-12-29
Contact: XIN Jia-ying E-mail:xinjiaying@yahoo.com.cn

摘要/Abstract

摘要： 人乳脂替代品的脂肪酸组成和结构与人乳脂相似，具有良好的发展前景。本文在介绍人乳脂中甘三酯的结构、组成和含量的特异性及婴儿对乳脂消化吸收特点的基础上，综述酶法生产人乳脂替代品的反应底物、脂肪酶、反应体系、检测方法的选择及近年来的研究进展，并对人乳脂替代品的研究前景进行展望。

中图分类号:

TS22
TS252

张超越辛嘉英王艳陈林林. 酶法制备人乳脂替代品的研究进展[J]. 食品科学, 2013, 34(3): 298-302.

[1]HAN N S, KIM T J, PARK Y C, et al. .Biotechnological production of human milk oligosaccharides[J].Biotechnology Advances,2011,:1-11
[2]YüKSEL A, YESILCUBUK N S.Enzymatic production of human milk fat analogues containing stearidonic acid and optimization of reactions by response surface methodology[J].Food Science and Technology,2012,46:210-216
[3]NAGACHINTA S, AKOH C C.Enrichment of palm olein with long chain polyunsaturated fatty acids by enzymatic acidolysis[J].LWT - Food Science and Technology,2012,46:29-35
[4]KOLETZKO B, PALMERO M R, DEMMELMAIR H, et al.Physiological aspects of human milk lipids[J].Early Human Development,2001,65:3-18
[5]SPITZER J, DOUCET S, BUETTNER A.The in?uence of storage conditions on ?avour changes in human milk[J].Food Quality and Preference,2010,21:998-1007
[6]YANG Tiankui, XU Xuebing, HE Chuan, et al.Lipase-catalyzed modi?cation of lard to producehuman milk fat substitutes[J].Food Chemistry,2003,80:473-481
[7]JIME′NEZ M J, ESTEBAN L, ROBLES A, et al.Production of triacylglycerols rich in palmitic acid at position 2 as intermediates for the synthesis of human milk fat substitutes by enzymatic acidolysis[J].Process Biochemistry,2010,45:407-414
[8]MUN?I′O M M, ROBLES A, ESTEBAN L, et al.Synthesis of structured lipids by two enzymatic steps: Ethanolysis of fish oils and esterification of 2-monoacylglycerols[J].Process Biochemistry,2009,44:723-730
[9]赵海珍,陆兆新,别小妹,等.高效液相色谱法测定猪油甘油三酯中的脂肪酸位置分布[J].色谱,2005,23(2):142-145
[10]ROBLES A, JIME′NEZ M J, ESTEBAN L, et al.Enzymatic production of human milk fat substitutes containing palmitic and docosahexaenoic acids at sn-2 position and oleic acid at sn-1,3 positions[J].LWT - Food Science and Technology,2011,44:1986-1992
[11]SAHIN N, AKOH C C,KARAALI A.Lipase-Catalyzed Acidolysis of Tripalmitin with Hazelnut Oil Fatty Acids and Stearic Acid To Produce Human Milk Fat Substitutes[J].Food Chem,2005,53:5779-
[12]NIELSEN N S ,YANG Tiankui, Xu Xuebing , et al.Production and oxidative stability of a human milk fat substitute produced from lard by enzyme technology in a pilot packed-bed reactor[J].Food Chemistry,2006,94:53-60
[13]韩瑞丽,马健,张佳程,等.棕榈酸在甘油三酯中的位置分布对婴儿营养吸收的影响[J].中国粮油学报,2009,24(5):81-83
[14]商允鹏,生庆海,王贞瑜,等.三酰甘油Sn-2位上棕榈酸生理功能及研究概况[J].中国粮油学报,2010,25(10):119-123
[15]何川.人乳脂脂肪酸组成及其制备方法研究进展[J].粮食与油脂,2004,3:17-19
[16]KONTKANEN H, ROKKA S, KEMPPINEN A, et al.Enzymatic and physical modification of milk fat: A review[J].International Dairy Journal,2011,21:3-13
[17]JEAN C M, PHILIPPE B.Triayclglycerol Structure of Human Colostrum and Mature Milk[J][J].American Oil Chemists’Society,1993,28(7):637-
[18]赵亚东, 霍贵成.固定化脂肪酶催化酯交换制备母乳脂肪替代物[J].油脂加工,2010,35(12):12-15
[19]SILVA R C, COTTING L N,POLTRONIERI T P, et al.The effects of enzymatic interesterification on the physical-chemical properties of blends of lard and soybean oil[J].Food Science and Technology,2009,42:1275-1282
[20]SERIBURI V, AKOH C C.Enzymatic Interesterification of Lard and High-Oleic Sunflower Oil with Candida Antarctica Lipase to Produce Plastic Fats[J].JAOCS,1998,75(10):1339-1345
[21]韩露露,李晓东.酶法生产人乳脂替代品技术研究进展[J].中国乳品工业,2009,37(8):41-44
[22]ZHAO Haizhen, Lu Zhaoxin, Lu Fengxia, et al.Lipase-catalysed acidolysis of lard with caprylic acid to produce structured lipid[J].International Journal of Food Science and Technology,2006,41:1027-1032
[23] 赵海珍.脂肪酶催化猪油酸解制备功能性脂的研究[D] .南京: 南京农业大学, 2005
[24]CURTIS J M, BERRIGAN N, DAUPHINEE P.The Determination of n-3 Fatty Acid Levels in Food Products Containing Microencapsulated Fish Oil Using the One-Step Extraction Method[J].Part 1: Measurement in the Raw Ingredient and in Dry Powdered Foods. J Am Oil Chem Soc,2008,85:297-305
[25]徐同成.null王文亮,程安玮,等.甘油三酯中脂肪酸分布位置检测方法研究进展[J].. 油脂工程技术,2010,:-
[26]TECELAO C, SILVA J, DUBREUCQ E, et al.Production of human milk fat substitutes enriched in omega-3 polyunsaturated fatty acids using immobilized commercial lipases and Candida parapsilosis lipase/acyltransferase[J].Journal of Molecular Catalysis B: Enzymatic,2010,65:122-127
[27]JIME′NEZ M J, ESTEBAN L, ROBLES A, et al.Production of triacylglycerols rich in palmitic acid at sn-2 position by lipase-catalyzed acidolysis[J].Biochemical Engineering Journal,2010,51:172-179
[28]ESTEBAN L, JIME′NEZ M J, HITA E, et al.Production of structured triacylglycerols rich in palmitic acid at sn-2 position and oleic acid at sn-1,3 positions as human milk fat substitutes by enzymatic acidolysis[J].Biochemical Engineering Journalc,2011,54:62-69
[29]Li Yanqi, Mu Huiling, ANDERSEN J E T, et al.New human milk fat substitutes from butterfat to improve fat absorption[J].Food Research International,2010,43:739-744
[30]KARABULUT I, TURAN S, VURAL H, et al.Human Milk Fat Substitute Produced by Enzymatic Interesterification of Vegetable Oil Blend[J].Food Technol. Biotechnol,2007,45(4):434-438
[31]MADUKO C C, PARK Y W.Modification of fatty acid and sterol composition of caprine milk for use as infant formula[J].International Dairy Journal,2007,17:1434-1440
[32]BOURLIEU C,BOUHALLAB S,LOPEZ C.Biocatalyzed modifications of milk lipids: applications and potentialities[J].Food Science & Technology,2009,20:458-469