食品科学

• 基础研究 • 上一篇    下一篇

山楂果胶的抗氧化活性

董银萍,李拖平   

  1. 1.辽宁大学生命科学院,辽宁 沈阳 110036;2.辽宁大学食品科学系,辽宁 沈阳 110036
  • 出版日期:2014-02-13 发布日期:2014-03-17

Antioxidant Activity of Haw Pectin in vitro and in vivo

DONG Yin-ping, LI Tuo-ping   

  1. 1. College of Life Science, Liaoning University, Shenyang 110036, China;
    2. Department of Food Science, Liaoning University, Shenyang 110036, China
  • Online:2014-02-13 Published:2014-03-17

摘要:

目的:研究山楂果胶的体内外抗氧化活性。方法:离体条件测定山楂果胶对O2-·、DPPH自由基和·OH的清除能力;利用高脂小鼠模型考察山楂果胶在生物体内的总抗氧化能力。结果:山楂果胶离体条件对O2-·、DPPH自由基和·OH表现出显著的清除作用。山楂果胶能显著提高小鼠肝脏谷胱甘肽(glutathione,GSH)的含量和抗氧化酶类谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-Px)、超氧化物歧化酶(superoxide dismutase,SOD)和过氧化氢酶(catalase,CAT)的活性,并可显著降低小鼠肝脏丙二醛(malondialdehyde,MDA)的含量。结论:山楂果胶具有显著的体内外抗氧化活性,在功能食品等领域具有良好的应用前景。

关键词: 山楂果胶, 抗氧化, 脂质过氧化

Abstract:

Objective: To explore the antioxidant activity of haw pectin in vitro and in vivo. Methods: The free radical
scavenging activities of haw pectin on superoxide anion, DPPH and hydroxyl radicals were detected. The in vivo antioxidant
activity was investigated in high-fat-diet-fed mouse model. Results: Haw pectin showed significant free radical scavenging
activities against all the three radical species. It also significantly increased the content of glutathione (GSH) and the
antioxidant enzyme activities of glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) and catalase (CAT).
Moreover, it significantly decreased malondialdehyde (MDA) content in the liver of mice. Conclusion: Haw pectin has great
potential for the development of functional foods due to its excellent antioxidant activity.

Key words: haw pectin, antioxidation, lipid peroxidization