食品科学

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microRNA与营养研究进展

满朝来,李 凤,唐高霞,甄 鑫,弭晓菊   

  1. 哈尔滨师范大学生命科学与技术学院,黑龙江 哈尔滨 150025
  • 出版日期:2014-11-15 发布日期:2014-11-06

microRNAs and Nutrition

MAN Chao-lai, LI Feng, TANG Gao-xia, ZHEN Xin, MI Xiao-ju   

  1. College of Life Science and Technology, Harbin Normal University, Harbin 150025, China
  • Online:2014-11-15 Published:2014-11-06

摘要:

microRNA(miRNA)是参与转录后调控的一类非编码小RNA分子,许多营养元素能够影响和调控miRNA的表达活性,进而间接发挥生物学作用。本文简要总结miRNA的表达与功能,同时概述食物来源miRNA的生物学意义,以及营养元素对机体内源miRNA表达活性的影响,最后对营养元素影响miRNA表达活性的可能应用前景也进行简单探讨,以期为miRNA在营养学理论和实践中的深入研究和应用提供参考。

关键词: microRNA, 营养, 表达, 肿瘤

Abstract:

microRNAs (miRNAs) are a family of important small non-coding RNA molecules, which participate in posttranscriptional
control of gene expression. A number of nutrient elements can play biological roles by affecting and
regulating the expression and activities of miRNAs. In this review, we briefly summarize the sources and functions of
miRNAs. Also, we analyze the biological significances of food-derived miRNAs, and the influences of nutrient elements
on endogenous miRNAs expression. Additionally, the possible applications of miRNAs expression affected by nutrient
elements are also discussed. We hope that this paper can provide references for further study and applications of miRNAs in
the field of nutritional science.

Key words: microRNAs, nutrition, expression, tumor

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