食品科学

• 专题论述 • 上一篇    下一篇

L-肉碱的生理功能、生物学制备及检测方法研究进展

杨月英1,黄娇芳2,3,顾金杰2,史吉平2,王红英1,*   

  1. 1.大连工业大学生物工程学院,辽宁 大连 116034;2.中国科学院上海高等研究院,生物炼制实验室,上海 201210;
    3.上海科技大学物质科学与技术学院,生物灵感工程实验室,上海 201210
  • 出版日期:2015-03-15 发布日期:2015-03-17

Advances in Physiological Functions, Biotransformation and Detection of L-Carnitine

YANG Yueying1, HUANG Jiaofang2,3, GU Jinjie2, SHI Jiping2, WANG Hongying1,*   

  1. 1. College of Biological Engineering, Dalian Polytechnic University, Dalian 116034, China;
    2. Laboratory of Biorefinery, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China;
    3. Integrative Bio-inspired Molecular Engineering Laboratory, School of Physical Science and Technology, ShanghaiTech University,Shanghai 201210, China
  • Online:2015-03-15 Published:2015-03-17

摘要:

L-肉碱即左旋肉碱,又叫维生素BT,是一种广泛存在于动物、植物以及部分微生物体内的活性异构体,其主要功能是参与脂肪酸的代谢。近年来,L-肉碱越来越广泛地用于新型的功能食品和降血脂新药的开发,因此,其生产方法和检测都面临更高的技术要求。文章重点综述了L-肉碱的生理功能、生物法制备以及检测方法,并对其未来发展方向进行展望。

关键词: L-肉碱, 脂肪酸代谢, 生物合成法, 活性异构体, 检测

Abstract:

L-Carnitine, also named vitamin BT, is an active compound found in animals and vegetal tissues, as well as
in microorganisms. L-carnitine plays an important role in fatty acid metabolism. In recent years, L-carnitine has been
increasingly used as a novel food additive and clinically applied in reducing blood fat, so that the demand for L-carnitine is
increasing in the worldwide market, and the development of manufacturing and detection methods is needed. Herein, the
physiological functions, biotransformation and detection methods of L-carnitine are summarized, and the future directions of
L-carnitine are put forward in this review.

Key words: L-carnitine, fatty acid metabolism, biotransformation, active isomer, detection

中图分类号: