食品科学

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灵芝菌丝体液态发酵及多糖药理活性研究进展

陶如玉1,2,郝利民1,2,*,陈 强1,贾士儒2,*,张黎明2,王 旭1   

  1. 1.中国人民解放军总后勤部军需装备研究所,北京 100010;2.天津科技大学生物工程学院,天津 300457
  • 出版日期:2015-05-15 发布日期:2015-05-11

Recent Progress in Pharmacological Activities of Polysaccharides from the Mycelia of Liquid-Cultured Ganoderma lucidum

TAO Ruyu1,2, HAO Limin1,2,*, CHEN Qiang1, JIA Shiru2,*, ZHANG Liming2, WANG Xu1   

  1. 1. Institute of Quartermaster Equipment, General Logistics Department of People’s Liberation Army, Beijing 100010, China;
    2. College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China
  • Online:2015-05-15 Published:2015-05-11

摘要:

灵芝是一种珍贵的药食两用真菌,具有补中益气、滋补强壮、扶正固本、延年益寿等功效。灵芝多糖是从灵芝子实体或液态发酵灵芝菌丝体中提取分离而获得的多糖,具有抗肿瘤、免疫调节、保肝护肝、抗氧化、抗疲劳、清除自由基和抗衰老等药理活性。本文对近年来灵芝的液态发酵过程中菌种选育、培养基和发酵条件优化以及灵芝多糖的药理活性研究进行系统综述。

关键词: 灵芝菌丝体, 液态发酵, 灵芝多糖, 药理活性

Abstract:

Ganoderma lucidum is a mushroom widely used in China as a traditional Chinese medicine and healthy food
for thousands of years due to its promotion of longevity and health. Polysaccharides extracted from fruit bodies or liquidcultured
mycelia of G. lucidum have anti-tumor, immune-improving, liver-protecting, anti-oxidation, anti-fatigue, free
radical scavenging and anti-aging functions. In this paper, we provide a systematic review of studies on strain breeding
and culture medium and conditions optimization for the production of G. lucidum polysaccharides as well as their
pharmacological activities.

Key words: Ganoderma lucidum mycelia, liquid-state fermentation, Ganoderma lucidum polysaccharides, pharmacological activity

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