食品科学

• 专题论述 • 上一篇    下一篇

乳酸杆菌S-层蛋白的结构及免疫调控功能研究进展

张英春1,2,向鑫玲1,张兰威1,马 放2,李少慧1   

  1. 1.哈尔滨工业大学化工学院,黑龙江 哈尔滨 150090;2.哈尔滨工业大学市政环境工程学院,黑龙江 哈尔滨 150090
  • 出版日期:2016-02-15 发布日期:2016-02-26

A Review on the Structure and Immune Regulation Function of Lactobacillus S-Layer Protein

ZHANG Yingchun1,2, XIANG Xinling1, ZHANG Lanwei1, MA Fang2, LI Shaohui1   

  1. 1. School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin 150090, China;
    2. School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China
  • Online:2016-02-15 Published:2016-02-26

摘要:

本文综述了乳酸杆菌S-层蛋白的结构及功能,包括S-层蛋白对胆盐及消化酶的耐受能力、参与乳酸杆菌对宿主的黏附作用、抑制病原菌对宿主细胞的黏附及侵入作用。并且详细阐述了S-层蛋白对细胞信号通路的调节功能,证明S-层蛋白对于乳酸杆菌发挥免疫调节功能具有重要的作用。

关键词: 乳酸杆菌, S-层蛋白, 信号通路, 免疫调节

Abstract:

The structure and function of Lactobacillus S-layer protein are reviewed in this paper with special focus on its
tolerance to digestive enzymes and bile salts, involvement in host cell adhesion of Lactobacillus and role in inhibiting host
cell adhesion and intrusion by pathogens. Meanwhile, the regulatory effect of Lactobacillus S-layer protein on cell signaling
pathways is expounded. In conclusion, this review suggests that Lactobacillus S-layer protein plays an important role in the
immunoregulatory effect of Lactobacillus.

Key words: Lactobacillus, S-layer protein, signaling pathways, immunoregulation

中图分类号: