原花色素降血脂机制研究进展

doi:10.7506/spkx1002-6630-201613040

摘要/Abstract

摘要：

原花色素是以黄烷-3-醇为基本单元，在自然界中广泛存在的多酚类物质，具有多种生物活性。本文综述了原花色素如何调节甘油三酯和胆固醇代谢过程中的关键蛋白从而控制体内主要脂类的含量；此外，还总结了原花色素如何调节体质量、能量摄入以及通过调节AMP依赖蛋白激酶（adenosine 5’-monophosphate-activated proteinkinase，AMPK）信号通路影响能量消耗，进而综合调控体内血脂的含量，达到降低血脂的功能。

关键词: 原花色素, 甘油三酯, 胆固醇, AMP依赖蛋白激酶, 代谢

Abstract:

Proanthocyanidins are a class of polyphenols that consist of flavan-3-ols as their basic unit and exist in various
types of plants. In this review, the regulation of proanthocyanidins on the key proteins of the metabolism pathways of
triglycerides and cholesterol is summarized. Also, how proanthocyanidins regulate body weight, energy intake and energy
expenditure through adenosine 5’-monophosphate-activated protein kinase (AMPK) pathway to exert their hypolipidemic
effects is demonstrated with details as well.

Key words: proanthocyanidins, triglyceride, cholesterol, adenosine 5’-monophosphate-activated protein kinase (AMPK), metabolism

中图分类号:

TS201.4

张妤，李澜奇，龚辉，陈士国，叶兴乾. 原花色素降血脂机制研究进展[J]. 食品科学, doi: 10.7506/spkx1002-6630-201613040.

ZHANG Yu, LI Lanqi, GONG Hui, CHEN Shiguo, YE Xingqian. The Hypolipidemic Mechanism of Proanthocyanidins[J]. FOOD SCIENCE, doi: 10.7506/spkx1002-6630-201613040.

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