食品科学 ›› 2012, Vol. 33 ›› Issue (3): 267-271.doi: 10.7506/spkx1002-6630-201203056

• 专题论述 • 上一篇    下一篇

红景天苷生物合成的细胞与分子生物学研究进展

祝顺琴,刘万宏,戴传云   

  1. 1. 西南大学生命科学学院
    2. 重庆科技学院化学化工学院
  • 出版日期:2012-02-15 发布日期:2012-02-14
  • 基金资助:
    重庆市科学技术委员会自然科学基金计划资助项目(2010BB5296);重庆市教育委员会科技研究项目(KJ101401); 中央高校基本科研业务费专项资金资助项目(XDJK2011C017)

Advances in Studies on Cellular and Molecular Biology of Salidroside Biosynthesis

ZHU Shun-qin,LIU Wan-hong,DAI Chuan-yun   

  1. 1.College of Life Science, Southwest University, Chongqing 400715, China; 2. College of Chemistry and Chemical Engineering, Chongqing University of Science and Technology, Chongqing 401331, China
  • Online:2012-02-15 Published:2012-02-14

摘要: 红景天苷因其抗氧化、抗疲劳、延缓衰老等生物学功能成为当今天然产物研究的热门方向。本文综述了红景天苷生物合成途径及途径中的相关酶与基因;利用红景天愈伤组织和细胞培养生产红景天苷的方法,通过遗传转化获得毛状根生产红景天苷等细胞与分子生物学的研究。最后提出细胞工程和基因工程是解决药源缺乏的理想途径之一。

关键词: 红景天苷, 生物合成, 细胞工程, 基因工程

Abstract: Research into salidroside as a naturally occurring compound is a hot topic nowadays due to its multiple bioactivities such as antioxidant, anti-fatigue, and anti-aging functions. This review covers the following aspects of the cellular and molecular biology of salidroside biosynthesis: (1) biosynthesis pathways and related enzymes and genes; (2) salidroside production by Rhodiola rosea callus and cell culture; (3) salidroside production from hair roots obtained by genetic transformation. Therefore, cell engineering and genetic engineering strategies can provide suitable strategies to solve the lack of drug resources.

Key words: salidroside, biosynthesis, cell engineering, genetic engineering

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