食品科学 ›› 2012, Vol. 33 ›› Issue (5): 256-259.doi: 10.7506/spkx1002-6630-201205054

• 营养卫生 • 上一篇    下一篇

云芝多糖对运动训练大鼠脑组织抗氧化能力和ATPase活性的影响

习雪峰,王单一,熊正英4,张 林   

  1. 1.河南大学体育学院 2苏州大学体育学院 3.河南中医学院针灸推拿学院 4.陕西师范大学体育学院
  • 出版日期:2012-03-15 发布日期:2012-03-03

Effect of Krestin Polysaccharide on Antioxidant Capability and ATPase Activity in Brain Tissues of Rats with High Intensity Exercise

XI Xue-feng,WANG Dan-yi,XIONG Zheng-ying,ZHANG Lin   

  1. 1. College of Physical Education, Henan University, Kaifeng 475001, China; 2. College of Physical Education, Suzhou University, Suzhou 215021, China;3. Acupuncture and Tuina-Massage Institute, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China;4. College of Physical Education, Shaanxi Normal University, Xi,an 710062, China
  • Online:2012-03-15 Published:2012-03-03

摘要: 目的: 探讨云芝多糖对力竭运动大鼠脑组织的部分抗氧化酶活性和Na+,K+-ATP酶(Na+,K+-ATPase),Ca2+,Mg2+-ATP酶(Ca2+,Mg2+-ATPase)活性影响。方法:选取成年雄性SD大鼠24只。将大鼠随机分为3组:安静对照组8只,运动对照组8只,运动加药组8只,进行为期8周的大强度耐力跑台训练。测定大鼠脑组织部分抗氧化酶和Na+,K+-ATPase,Ca2+,Mg2+-ATPase活性的变化。结果:与安静对照组相比,运动对照组脑组织中超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-Px)、总抗氧化能力(T-AOC)、Na+, K+-ATPase、Ca2+,Mg2+-ATPase活性和血糖含量显著下降(P<0.01或P<0.05),MDA生成显著增多(P<0.05);云芝多糖提高了力竭运动大鼠脑组织SOD、CAT、GSH-Px、T-AOC、Na+,K+-ATPase、Ca2+,Mg2+-ATPase活性和血糖含量(P<0.01或P<0.05),减少MDA生成(P<0.05)。结论:云芝多糖可以提高力竭运动大鼠脑组织中抗氧化酶活性和Na+,K+-ATPase和Ca2+,Mg2+-ATPase的活性,这对于维持运动中能量的供应和抗氧化能力,从而提高大鼠的运动能力具有重要意义。

关键词: 云芝多糖, 抗氧化酶, 运动训练, 大鼠

Abstract: Objective: To explore the effect of Krestin polysaccharide (PSK) on the activities of antioxidant enzymes and Na+-K+-ATPase as well as Ca2 +-Mg2 +-ATPase in brain tissues of rats after exhaustive exercise. Methods: 24 SD rats were divided into three groups including the control group without exercise, exercise group and exercise plus PSK group. Each group included 8 rats. The rats from the exercise and exercise plus PSK groups were subjected to high-intensity endurance running for 8 consecutive weeks. The changes in the activities of antioxidant enzymes, Na+-K+-ATPase and Ca2+-Mg2+-ATPase were measured. Results: The activities of SOD, CAT, GSH-Px, T-AOC, Na+-K+-ATPase and Ca2+-Mg2+-ATPase as well as blood sugar revealed a significant decrease in exercise groups when compared with the control group without exercise (P<0.01 or P<0.05). Meanwhile, the generation of MDA exhibited a significant increase in exercise groups (P<0.05). Moreover, PSK could improve the activities of SOD, CAT, GSH-Px, T-AOC, Na+-K+-ATPase, Ca2+-Mg2+-ATPase and blood sugar in brain tissues of the rats with exhaustive exercise (P<0.01 or P<0.05), and reduce the MDA generation (P<0.05). Conclusion: PSK can improve the activities of antioxidant enzymes, Na+-K+-ATPase and Ca2+-Mg2+-ATPase in brain tissues of the rats with exhaustive exercise, which is important for keeping energy supply during the exercise and enhancing the exercise capacity of rats.

Key words: polysaccharide krestin (PSK), antioxidant enzymes, exercise training, rats

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