食品科学 ›› 2017, Vol. 38 ›› Issue (19): 301-308.doi: 10.7506/spkx1002-6630-201719047

• 专题论述 • 上一篇    下一篇

金属-有机骨架材料作为分离介质在食品生物分析中的应用

孟庆茹,姜子涛*,李 荣,汤书华   

  1. 天津商业大学生物技术与食品科学学院,天津市食品生物技术重点实验室,天津 300134
  • 出版日期:2017-10-15 发布日期:2017-09-29
  • 基金资助:
    天津市自然科学基金项目(12JCZDJC34100;13JCYBJC18700)

Application of Metal-Organic Framework Materials as Separation Medium in the Analysis of Food and Biological Samples

MENG Qingru, JIANG Zitao*, LI Rong, TANG Shuhua   

  1. Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin 300134, China
  • Online:2017-10-15 Published:2017-09-29

摘要: 金属-有机骨架材料(metal-organic frameworks,MOFs)具有比表面积大、热稳定性好、孔径尺寸可调 控、孔大小分布均匀、表面修饰可调控等特性。简述了MOFs的研究概况,论述了其作为分离介质的优点,综述了 近几年其在磷酸肽、抗生素、食品添加剂、食品农药残留、有机污染物等的分析和在气体吸附、传感器中的应用。 在未来,利用MOFs得到的氧化物可作为色谱固定相,应用在色谱仪器中分析生物大分子,也可以制备具有磁性的 MOFs,用于蛋白质的分离提取等,这表明MOFs在食品生物分析领域具有良好的应用前景。

关键词: 金属-有机骨架材料(MOFs), 分离富集, 食品生物分析

Abstract: Metal-organic frameworks (MOFs) have a series of features such as large specific surface area, good thermal stability, adjustable aperture size, uniform pore size distribution, and controllable surface modification. In this paper, we present a brief overview of recent studies on MOFs with focus on their advantages in use as a separation medium, and their applications in the analysis of phosphopeptides, antibiotics, food additives and pesticide residues in foods, the separation of organic pollutants, gas adsorption and sensing. In the future, MOFs derived oxides will be used as a stationary phase for the chromatographic separation of biological macromolecules and magnetic MOFs will be used for the separation and extraction of proteins. MOFs will have a bright application prospect in the analysis of food and biological samples.

Key words: metal-organic frameworks (MOFs), separation and enrichment, analysis of food and biological samples

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