食品科学 ›› 2018, Vol. 39 ›› Issue (5): 239-246.doi: 10.7506/spkx1002-6630-201805036

• 营养卫生 • 上一篇    下一篇

利用燕麦麸脂肪模拟物制作的发酵香肠对大鼠血脂水平及血清抗氧化性能的影响

杨 敏1,杨 勇1,*,吴世涛2,李彬彬1,张 楠1,张学广1,侯 青1,陈 洪1,林德荣1,刘爱平1,刘韫涛1,李 健3,林 燕3   

  1. 1.四川农业大学食品学院,四川 雅安 625014;2.四川农业大学动物科技学院,四川 雅安 625014;3.四川农业大学动物营养研究所,四川 雅安 625014
  • 出版日期:2018-03-15 发布日期:2018-03-14
  • 基金资助:
    四川农业大学2016年学科建设双支计划项目(03572094)

Effect of Consumption of Fermented Sausage Made with Oat Bran-Supplemented Fat Simulant on Lipid Levels and Serum Antioxidant Status in Rats

YANG Min1, YANG Yong1,*, WU Shitao2, LI Binbin1, ZHANG Nan1, ZHANG Xueguang1, HOU Qing1, CHEN Hong1, LIN Derong1, LIU Aiping1, LIU Yuntao1, LI Jian3, LIN Yan3   

  1. 1. College of Food Science, Sichuan Agricultural University, Ya’an 625014, China; 2. College of Animal Science and Technology, Sichuan Agricultural University, Ya’an 625014, China; 3. Animal Nutrition Institute, Sichuan Agricultural University, Ya’an 625014, China
  • Online:2018-03-15 Published:2018-03-14

摘要: 本实验旨在研究利用燕麦麸脂肪模拟物制作的发酵香肠(oat bran-supplemented fat simulant,OBFS)与 传统发酵香肠(traditional fermented sausage,TFS)对正常大鼠血脂水平及血清抗氧化性能的影响。选取平均体质 量为(70±2)g的健康Sprague-Dawley(SD)大鼠51 只,随机分成3 组,各组分别饲喂在基础饲料中添加0%(质 量分数,下同)的OBFS及TFS(基础组)、20%的TFS(对照组)、20%的OBFS(实验组)的饲料,分别在第0、 3、6、9周测定大鼠的空腹血清总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、低密度脂蛋白 胆固醇(low density lipoprotein cholesterol,LDL-C)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol, HDL-C)、丙二醛(malonaldehyde,MDA)含量、氧化低密度脂蛋白(oxidized low density lipoprotein,ox-LDL) 质量浓度以及超氧化物歧化酶(superoxide dismutase,SOD)水平。结果显示:与基础组相比,实验组大鼠的 采食量在第6、9周时显著降低(P<0.05),体质量在第3周时显著升高(P<0.05),第6、9周时无显著性差异 (P>0.05);TC、TG、LDL-C含量在第3、6、9周时偏低,HDL-C含量在第6周时显著降低(P<0.05),第3、9 周时无显著性差异(P>0.05);ox-LDL质量浓度、MDA含量在第3、6、9周时无显著性差异(P>0.05),SOD 水平在第9周时显著升高(P<0.05)。与对照组相比,实验组大鼠的采食量在第3、6、9周时偏低,体质量在第9 周时显著降低(P<0.05),TC、TG、LDL-C含量在第3、6、9周时无显著性差异(P>0.05),HDL-C含量偏高, ox-LDL质量浓度在第3周时显著升高(P<0.05),MDA含量在第3、6、9周无显著性差异(P>0.05),SOD水平 在第9周时显著升高(P<0.05)。证明相比于TFS而言,OBFS具有抑制食欲、控制体质量、促进血清中胆固醇及 TG的排除和增强血清清除自由基及抗氧化活性的作用。

关键词: 燕麦麸脂肪模拟物, 发酵香肠, 大鼠, 血脂, 脂质过氧化

Abstract: Objective: To study the effect of the ingestion of fermented sausage formulated with oat bran-supplemented fat simulant (OBFS) against traditional fermented sausage (TFS) on lipid levels and antioxidant status in rats. Methods: A total of fifty-one healthy rats with average body weight of (70 ± 2) g were randomly divided into 3 groups: blank, control and experimental groups, which were fed on a basal diet alone or supplemented with 20% OBFS and 20% TFS, respectively. The levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), oxidized low density lipoprotein (ox-LDL), malonaldehyde (MDA) and superoxide dismutase (SOD) activity in serum were measured at the end of 0, 3, 6 and 9 weeks. Results: Compared with the blank group, feed intake significantly decreased after 6 and 9 weeks in the experimental group (P < 0.05); body weight significantly increased after 3 weeks (P < 0.05), but no significant difference was noted after 6 and 9 weeks (P > 0.05); serum TC, TG and LDL-C were lower but not significantly different at all three time points (P > 0.05); HDL-C significantly decreased after 6 weeks (P < 0.05), but no significant difference was observed at other time points (P > 0.05); there was no significant difference in ox-LDL or MDA content at three time points (P > 0.05); SOD activity significantly increased after 9 weeks (P < 0.05). Compared with the comparison group, feed intake decreased after 3, 6 and 9 weeks in the experimental group, but was not significantly different (P > 0.05); body weight significantly decreased after 9 weeks (P < 0.05); TC, TG and LDL-C were not significantly different at three time points (P > 0.05); HDL-C increased but not statistically significantly after 6 weeks (P > 0.05); ox-LDL significantly increased after 3 weeks (P < 0.05); no significant difference in MDA was found at all three time points (P > 0.05); SOD activity significantly increased after 9 weeks (P < 0.05). Conclusion: Compared with TFS, OBFS could suppress appetite, control body weight, enhance serum TC and TG metabolism and increase serum antioxidant status.

Key words: oat bran-supplemented fat simulant, fermented sausage, rats, lipids, lipid oxidation

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