食品科学 ›› 2011, Vol. 32 ›› Issue (11): 318-323.doi: 10.7506/spkx1002-6630-201111067

• 专题论述 • 上一篇    下一篇

酿酒酵母中的谷氨酰转肽酶研究进展

张媛媛,郑飞云,李永仙,顾国贤,李崎   

  1. 1.江南大学 工业生物技术教育部重点实验室 2.江南大学生物工程学院
  • 出版日期:2011-06-15 发布日期:2011-05-13
  • 基金资助:
    “十一五”国家科技支撑计划项目(2008BAI63B06)

Recent Progress of Research on Gamma-Glutamyltranspeptidase in Saccharomyces cerevisiae

ZHANG Yuan-yuan1,2,ZHENG Fei-yun1,2,LI Yong-xian1,2,LI Qi1,2,*,GU Guo-xian2   

  1. 1. Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University,Wuxi 214122, China ; 2. School of Biotechnology, Jiangnan University, Wuxi 214122, China
  • Online:2011-06-15 Published:2011-05-13

摘要: 介绍谷氨酰转肽酶(γ-GT)的研究概况,重点综述酿酒酵母中谷氨酰转肽酶的结构以及催化机制。酿酒酵母γ-GT在细胞中与谷胱甘肽水平的高低有密切关系,并在酵母细胞解毒或抗外界胁迫及液泡氨基酸转运的过程起着重要作用。目前,γ-GT在临床医学和工农业中有着重要的地位,并对细胞内解毒重要物质--谷胱甘肽的含量有着重要的影响。

关键词: 酵母, 谷氨酰转肽酶, 谷胱甘肽, Ycf1

Abstract: The current status of the research on γ-glutamyltranspeptidase (γ-GT) in Saccharomyces cerevisiae is presented in this paper, especially the structure and catalytic mechanisms of γ-GT. γ-GT highly affects the amount of intracellular glutathione in Saccharomyces cerevisiae cells, and plays an important role for the detoxication, resistance to environment stress, and amino acid transportation in S. cerevisiae. Now γ-GT also contains important significance in clinical medicine and the fields of agriculture and industry.

Key words: yeast, glutamyltranspeptidase, glutathione, Ycf1

中图分类号: