食品科学 ›› 2011, Vol. 32 ›› Issue (17): 317-320.doi: 10.7506/spkx1002-6630-201117066

• 营养卫生 • 上一篇    下一篇

普洱茶对高脂血症大鼠血脂、血浆中血栓素B2,6-酮前列腺素F1α水平影响

江新凤1,邵宛芳2,*   

  1. 1.江西省蚕桑茶叶研究所 2.云南农业大学龙润普洱茶学院
  • 发布日期:2011-08-30
  • 基金资助:
    国家现代农业(茶叶)产业技术体系建设专项(CARS-23);云南省生物资源创新办科技项目(2007YNCXB-01-01); “十一五”国家科技支撑计划项目(2007BAD58B04)

Effect of Pu-erh Tea on Blood Lipid and Plasma TXB2 and 6-Keto-PGF1α Levels in Hyperlipidemic Mice

JIANG Xin-feng1,SHAO Wan-fang2,*   

  1. (1. Jiangxi Sericulture and Tea Research Institute, Nanchang 330202, China; 2. College of Longrun Pu-erh Tea,Yunnan Agricultural University, Kunming 650201,China)
  • Published:2011-08-30

摘要: 采用高脂饲料饲喂法建立高脂血症大鼠模型,同时以0.5、1.0、2.0g/(kg ·d) 3种普洱茶的剂量饲喂昆明种SPF级雌性大鼠35d后,检测大鼠血液总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)的含量,采用ELISA法定量测定大鼠血浆血栓素B2(thromboxaneB2,TXB2)、6-酮前列腺素F1α(6-keto-PGF1α)的含量。结果表明,普洱茶能明显降低模型大鼠血液TG、TC、LDL-C、TXB2含量,提高HDL-C、6-keto-PGF1α含量。

关键词: 普洱茶, 高脂血症, 血栓素B2, 6-酮前列腺素F1α

Abstract: In order to establish a hyperlipidemic mouse model by feeding high-fat diet, SD mice fed Pu-erh tea at the dosages of 0.5, 1.0 g/(kg ·d) and 2.0 g/(kg ·d) for 35 consecutive days. The total cholesterol (TCHO), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) in the blood of SD mice were determined. Meanwhile, plasma thromboxane-B2 (TXB2) and 6-keto-prostaglandin F1α (6-keto-PGF1α) were also analyzed by ELISA. The results showed that the levels of TCHO, TC, LDL-C and TXB2 in SD mouse blood exhibited a significant reduction in treatment groups while HDL-C and 6-keto-PGF1α revealed a significant increase (P<0.05; P<0.01) when compared with the control group.

Key words: Pu-erh tea, hyperlipidemia, thromboxane B2 (TXB2), 6-keto-PGF1α

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