食品科学 ›› 2011, Vol. 32 ›› Issue (18): 209-213.doi: 10.7506/spkx1002-6630-201118045

• 分析检测 • 上一篇    下一篇

莱克多巴胺在猪不同可食组织中的残留

路 勇1,2,张卫民2,黄 华2,赵雅松2,吴 颖3,汪 明1,*   

  1. 1. 中国农业大学动物医学院
    2.北京市食品安全监控中心 3.北京市产品质量监督检验所
  • 出版日期:2011-09-25 发布日期:2011-09-24
  • 基金资助:
    北京奥科委、北京市科委“奥运食品中兴奋剂类物质检测、监控技术研究”专项

Metabolism of Ractopamine Residues in Edible Pork Tissues after Withdrawal

LU Yong1,2,ZHANG Wei-min2,HUANG Hua2,ZHAO Ya-song2,WU Ying3,WANG Ming1,*   

  1. (1. College of Veterinary Medicine, China Agricultural University, Beijing 100094, China; 2. Beijing Municipal Center for Food Safety Monitoring, Beijing 100041, China; 3. Beijing Products Quality Supervision and Inspection Institute, Beijing 100013, China)
  • Online:2011-09-25 Published:2011-09-24

摘要: 系统研究莱克多巴胺(RCT)在猪可食组织中的残留代谢规律。对60头健康猪以25mg/kg的剂量混饲给药8d。在停药1、2、3、4、5、6、7、8、9、14、21d和28d分别屠宰3头猪,取猪里脊等可食用组织和尿液利用快速检测前处理试剂盒-超高效液相色谱/串联质谱法测定残留量。结果显示:猪肾脏中残留量最高,停药1d时平均残留量为96.3μg/kg;肝脏其次,停药1d时平均残留量为67.7μg/kg;猪后臀尖肉再次,停药1d时平均残留量为15μg/kg;猪里脊肉中残留量最少,停药1d时平均残留量仅为8.9μg/kg。肾脏、肝脏和猪里脊肉中RCT均在停药9d后降至检测限以下,而后臀尖肉中RCT在停药7d后降至检测限以下。

关键词: 莱克多巴胺, 猪可食组织, 残留代谢规律

Abstract: The distribution and elimination of ractopamine residues in edible pork tissues were investigated. At a dosage of 26 mg/ kg, ractopamine was added to the feed for 60 healthy pigs. Three pigs were slaughtered at 1, 2, 3, 4, 5, 6, 7, 8, 9, 14, 21 and 28 d after withdrawal, respectively, and edible tissues and urine were collected to determine ractopamine residues in them by rapid pretreatment kits and ultra performance liquid chromatography coupled with tandem mass spectrometry (UPLC/MS-MS). Ractopamine showed an average residue of 96.3, 67.7, 15μg/kg and 8.9μg/kg in kidney, liver, rump and tenderloin at 1 day after withdrawal, respectively. The ractopamine residues in kidney, liver and tenderloin decreased to less than the detection limit on the 9th day compared to the 7th day observed for rump.

Key words: ractopamine (RCT), edible pork tissues, residue metabolism

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