关键词: 液相色谱串联质谱, 啶酰菌胺, 环酰菌胺, 蔬菜, 水果

Abstract: A liquid chromatography-tandem mass spectrometry method was established to determine boscalid and fenhexamid residues in fruits and vegetables. Analytes were extracted from samples using 1% acetic acid acetonitrile, and then purified by solid phase extraction cartridge packaged with sorbent primary secondary amine (PSA) and C18. The residues were determined by high-performance liquid chromatography coupled with tandem MS (HPLC-MS/MS) using external standard method, and the interference of matrix was deducted by the matrix-matched calibration standards curve. A good linearity of calibration curve was exhibited over a concentration range of 1μg/L to 100μg/L for boscalid and fenhexamid with a correlation coefficient of 0.9996 and 0.9997, respectively. Average recoveries for boscalid and fenhexamid in 4 samples at spiked levels of 5－50μg/kg were between 77.7% and 93.8%, with a relative standard deviations between 2.1% and 6.3%. For boscalid and fenhexamid, the limit of quantification were 1.32, 1.20μg/kg and the limit of detection were 0.395, 0.361μg/kg, respectively.

Key words: HPLC-MS/MS, boscalid, fenhexamid, fruits, vegetables