蛋清肽- 钙配合物体内促钙吸收作用研究

doi:10.7506/spkx1002-6630-201211055

食品科学 ›› 2012, Vol. 33 ›› Issue (11): 262-265.doi: 10.7506/spkx1002-6630-201211055

蛋清肽- 钙配合物体内促钙吸收作用研究

韩樱，何慧*，赵宁宁，李江涛，王真真，聂志奎

华中农业大学食品科学技术学院

出版日期:2012-06-15 发布日期:2012-07-27

Effect of Egg White Peptide Binding with Calcium on Promotion of Calcium Absorption in vivo

HAN Ying，HE Hui*，ZHAO Ning-ning，LI Jiang-tao，WANG Zhen-zhen，NIE Zhi-kui

(College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China)

Online:2012-06-15 Published:2012-07-27

摘要/Abstract

摘要： 目的：为了考察蛋清肽-钙配合物(EWP-Ca)在动物体内的补钙效果。方法：将60只Wistar雄性大鼠随机分为6组：普通组、缺钙模型组、CaCO3组以及低、中、高剂量EWP-Ca组，通过构造缺钙大鼠模型，进行了为期30d的补钙实验，实验结束后对各种与补钙相关的指标进行测定。结果：与缺钙模型组相比，高剂量EWP-Ca组(Ca剂量为106.4mg/(kg ·d))能极显著增加大鼠股骨直径、干质量、骨钙含量及股骨密度(P＜0.01)，极显著降低血清碱性磷酸酶(AKP)活力(P＜0.01)；与钙含量相同的CaCO3组相比，EWP-Ca高剂量组股骨直径、骨钙含量极显著和显著增加(P＜0.01，P＜0.05)。结论：EWP-Ca具有体内促进钙吸收作用，且效果优于钙含量相同的CaCO3。

关键词: 蛋清肽, 蛋清肽-钙配合物, 促钙吸收, 补钙制剂

Abstract: Objective: To explore the promoting effect of egg white peptide binding with calcium (EWP-Ca) on calcium absorption in vivo. Methods: Totally 60 male Wistar rats were randomly divided into 6 groups: normal group, calcium-deficient model group, CaCO3 group and EWP-Ca groups at low, medium and high doses. Calcium-deficient model rats were fed a low-Ca diet, and calcium absorption-related indices were determined after a feeding period of 30 days. Results: EWP-Ca at high dose (106.4 mg/(kg ·d)) could significantly increase femur diameter, dry weight, calcium content and bone mineral density (P＜0.01) and could significantly decrease the activity of serum alkaline phosphatase (AKP) (P＜ 0.01) when compared with calcium-deficient model control group. Moreover, compared with CaCO3 group at the same calcium level, femur diameter (P＜0.01) and bone calcium content (P＜0.05) were significantly increased. Conclusion: EWP-Ca can promote calcium absorption in vivo, which is better than CaCO3 at the same calcium level.

Key words: egg white peptide, egg white peptide binding with calcium (EWP-Ca), calcium absorption-promoting effect, calcium supplement

中图分类号:

TS253.9

韩樱，何慧，赵宁宁，李江涛，王真真，聂志奎. 蛋清肽- 钙配合物体内促钙吸收作用研究[J]. 食品科学, 2012, 33(11): 262-265.

HANYing，HEHui，ZHAONing-ning，LIJiang-tao，WANGZhen-zhen，NIEZhi-kui. Effect of Egg White Peptide Binding with Calcium on Promotion of Calcium Absorption in vivo[J]. FOOD SCIENCE, 2012, 33(11): 262-265.

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蛋清肽- 钙配合物体内促钙吸收作用研究

Effect of Egg White Peptide Binding with Calcium on Promotion of Calcium Absorption in vivo

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