食品科学 ›› 2019, Vol. 40 ›› Issue (9): 302-308.doi: 10.7506/spkx1002-6630-20180131-441

• 专题论述 • 上一篇    下一篇

原花青素防治II型糖尿病的研究进展

刘 丹1,邓建军2,张 超1,张敬华1,杨海霞1,*   

  1. 1.西安交通大学医学部公共卫生学院,陕西 西安 710061;2.西北大学化工学院,陕西 西安 710069
  • 出版日期:2019-05-15 发布日期:2019-05-28
  • 基金资助:
    国家自然科学基金面上项目(21676212)

Recent Advances of Procyanidins in Prevention and Control of Type II Diabetes

LIU Dan1, DENG Jianjun2, ZHANG Chao1, ZHANG Jinghua1, YANG Haixia1,*   

  1. 1. College of Public Health, Health Science Center, Xi’an Jiaotong University, Xi’an 710061, China; 2. School of Chemical Engineering, Northwest University, Xi’an 710069, China
  • Online:2019-05-15 Published:2019-05-28

摘要: 糖尿病是一种常见的慢性代谢性疾病,已成为继恶性肿瘤和心脑血管疾病之后的第三大疾病,其中II型糖尿病发病最为普遍,其发病机制目前尚不明确。原花青素是一种来源广泛、安全度高、生物活性优良的天然植物化学物,具有良好的抗糖尿病作用。本文系统综述了原花青素对II型糖尿病防治作用的研究进展及潜在的作用机制。

关键词: 植物化学物, 原花青素, II型糖尿病, 作用机制

Abstract: Diabetes mellitus, one of the most common chronic metabolic diseases, has become the third major disease after malignant tumor and cardiovascular and cerebrovascular diseases. Type II diabetes mellitus (T2DM) is the most prevalent form of diabetes. However, the pathogenesis of T2DM is still unclear so far. Procyanidins, a group of natural phytochemicals with a wide range of sources, high safety and good biological activity, can exert antidiabetic effect. The potential mechanism of action of procyanidins in the prevention and control of T2DM is systematically reviewed in this article.

Key words: phytochemicals, procyanidins, type II diabetes, mechanism

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