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植物多酚与肠道微生物群的相互作用及其对代谢性疾病影响的研究进展

赵媚,常凌,宋泽和,贺喜   

  1. 湖南农业大学
  • 收稿日期:2020-02-29 修回日期:2021-01-30 出版日期:2021-03-15 发布日期:2021-03-22
  • 通讯作者: 宋泽和 E-mail:zehesong111@163.com
  • 基金资助:
    湖南农业大学重大科研项目暨创新团队培育工程资助项目;湖南农业大学“双一流”建设项目;国家重点研发计划

Interactions between Plant Polyphenols and Intestinal Microbiota and Their Effects on Metabolic Diseases

1, 1   

  • Received:2020-02-29 Revised:2021-01-30 Online:2021-03-15 Published:2021-03-22

摘要: 摘 要:肠道微生物群参与胰岛素抵抗、高血糖、血脂异常、中心性肥胖和高血压等组成的代谢综合征的发展,进一步导致代谢性疾病的发生。而植物多酚可以促进肠道微生物群中有益菌的生长,间接减少致病菌的数量。并且肠道微生物群能够将高分子量的植物多酚代谢为更具生物活性的代谢物以提高其生物利用度。本文综述了植物多酚与肠道微生物群两者之间的相互作用及其对代谢性疾病的影响,为植物多酚的利用提供参考。

关键词: 关键词:植物多酚, 肠道微生物群, 代谢性疾病, 代谢综合征, 肥胖

Abstract: Abstract: Intestinal microflora is involved in the development of metabolic syndrome, which is composed of insulin resistance, hyperglycemia, dyslipidemia, central obesity and hypertension. Plant polyphenols can promote the growth of beneficial bacteria in intestinal microflora and indirectly reduce the number of pathogenic bacteria. Moreover, intestinal microbiota can metabolize high molecular weight plant polyphenols into more bioactive metabolites to improve their bioavailability. In this paper, the interaction between plant polyphenols and intestinal microflora and their effects on metabolic diseases are reviewed, which can provide reference for the utilization of plant polyphenols.

Key words: Keywords: plant polyphenols, intestinal microflora, metabolic diseases, metabolic syndrome, obesity

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